首页|基于中医传承计算平台分析李宗智治疗黄斑病变的用药规律

基于中医传承计算平台分析李宗智治疗黄斑病变的用药规律

扫码查看
目的 基于中医传承计算平台挖掘李宗智治疗黄斑病变的用药规律.方法 收集2020年1月1日至2022年10月27日李宗智治疗黄斑病变的有效医案,运用中医传承计算平台(V3.0)软件对处方数据进行药物频次、四气、五味、归经等统计,采用关联规则、聚类分析等进行数据挖掘.结果 共纳入处方286首,涉及药物60味,使用频次100次以上的药物共9味,分别是决明子、淡竹叶、山药、女贞子、麦冬、茺蔚子、连翘心、山枝仁、石斛;药性多寒,药味多甘,多归肝经,胃经、肾经次之;功效归类以补虚药为主,清热药次之.关联分析得到7对常用药对,药物关联规则5组,核心药物4味;聚类分析得出3组核心药物.结论 李宗智治疗黄斑病变以"清补肝肾阴"为法,补虚与清热同用,补虚为主、清热为辅,佐以清心,体现李宗智攻补兼施的辨治思想和独到的用药特点.
Analysis of LI Zongzhi's Medication Rule in Treating Macular Degeneration based on the Traditional Chinese Medicine Inheritance Computing Platform
Objective To investigate the medication rule of Professor LI Zongzhi in the treatment of macular disease based on a traditional Chinese medicine inheritance computing platform.Method Effective medical re-cords of Professor LI's treatment of macular lesions from January 1,2020 to October 27,2022 were collected,and statistics of drug frequency,four Qi,five flavors,and normalization were performed on the prescription data using the Traditional Chinese Medicine inheritance Computing platform(V3.0)software.Association rules and cluster analysis were used for data mining.Results A total of 286 prescriptions were included,involving 60 kinds of drugs.Among them 9 kinds of drugs were used more than 100 times,which were cassia seed,bamboo leaf,yam,Ligustrum,Ophioponata,Leonurus japonica,forsythia core,Sanzhikern,and Dendrobium officina-lis.The medicinal properties are cold with sweet flavor,which mainly belong to the liver meridian,and followed by stomach,kidney meridian in turn.For the efficacy classifications,the drugs is mainly with the function of supplement deficiency,and followed by heat-clearing.Association analysis showed 7 pairs of common drugs,5 groups of drug association rules and 4 core drugs.Three groups of core drugs were obtained by cluster analysis.Conclusion Professor LI's treated macular disease with the method of"tonifying the Yin of liver and kidney".While treating,use the method of supplement deficiency mainly,together with the method of clearing heat for supplementing and clearing heart for assistant.It embodies LI Zongzhi's unique medication characteristics of tak-ing the method of simultaneous attack and supplementation in the treatment.

macular lesionsdrug use patterndata miningLI ZongzhiTCM inheritance computing plat-form

王光福、陈雪宝、罗文奎、孙兴利、谌洪俊

展开 >

贵州中医药大学,贵州贵阳 550025

厦门市同安区新美街道社区卫生服务中心,福建厦门 361100

贵州中医药大学第一附属医院,贵州贵阳 550001

黄斑病变 用药规律 数据挖掘 李宗智 中医传承计算平台

贵州省中医药管理局中医药民族医药科学技术课题研究资助项目

QZYY2017-093

2024

贵州中医药大学学报

贵州中医药大学学报

ISSN:
年,卷(期):2024.46(5)