Metabolic flux limit prediction based on Pareto frontier
Metabolic flux,an important indicator describing the metabolism within living organisms,is widely applied in fields such as medicine and bioengineering.Metabolic flux limits are crucial for re-vealing the mechanisms of chemical reactions in living organisms,predicting the metabolic characteris-tics of organisms'growth,and studying ecosystems.Calculating metabolic flux limits is extensively used in bio-manufacturing engineering,identifying disease treatment targets,and drug development.Howev-er,the current traditional methods for calculating metabolic flux limits solely rely on physicochemical constraints,and the obtained limits may not necessarily reflect real occurrences.In this paper,we intro-duce the concept of Pareto frontier in the population of organism evolution and predict metabolic flux limits by using known metabolic flux data.
NETL
NSTL
万方数据
维普
