首页|COVID-19患者肌少症的发生发展及运动改善机制研究进展

COVID-19患者肌少症的发生发展及运动改善机制研究进展

扫码查看
2019年始,新型冠状病毒疾病(Corona Virus Disease 2019,COVID-19)席卷世界,影响全球公众的健康安全与生活方式。由于各国的协同合作,陆续出现的疫苗和特效药物使其临床治愈率持续上升。然而,感染COVID-19后肌少症仍长期影响感染者的身体活动水平和生活质量。COVID-19的多系统症状与肌少症相互串扰,作为两者共效干预方式,运动对COVID-19感染期间获得性肌少症具有良好疗效。本研究立足于运动治疗COVID-19后肌少症的临床效果,对其可能存在的机制进行综述。结果表明,运动改善COVID-19后肌少症的潜在机制与免疫系统、线粒体功能、激素水平、肌卫星细胞、心理状况和肠道微生物群密切相关。
Occurrence and development of post-COVID-19 sarcopenia and the mechanism of improvement through exercise
The Corona Virus Disease 2019(COVID-19),prevalent since 2019,impacts global health,safety,and lifestyle.Due to the collaborative efforts of various countries,the emergence of vaccines and specific drugs has led to a continuous increase in clinical cure rates.However,post-COVID-19 sarcopenia remains a persistent challenge im-pacting affected individuals'physical activity and overall quality of life.COVID-19 multi-system symptoms and sarco-penia mutually interfere with each other,in a co-effective intervention approach.Exercise shows a good therapeutic ef-fect on post-COVID-19 sarcopenia.This article focuses on the clinical efficacy of exercise therapy for sarcopenia after COVID-19,and reviews the possible mechanisms involved.The results indicate that the potential mechanisms by which exercise improves post-COVID-19 sarcopenia are closely related to the immune system,mitochondrial function,hor-mone levels,muscle satellite cells,psychological status,and gut microbiota.

COVID-19SarcopeniaExerciseMechanism

厚双龙、潘义、赵鑫、王刚

展开 >

西安体育学院研究生部,陕西 西安 710068

海宁市第二人民医院,浙江 海宁 314400

西安体育学院运动与健康科学学院,陕西 西安 710068

新型冠状病毒疾病 肌少症 运动 机制

2024

海南医学
海南省医学会

海南医学

影响因子:1.158
ISSN:1003-6350
年,卷(期):2024.35(5)
  • 58