首页|早期乳腺癌患者整形保乳术与常规保乳术对美容效果和生存预后的比较研究

早期乳腺癌患者整形保乳术与常规保乳术对美容效果和生存预后的比较研究

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目的 比较整形保乳术与常规保乳术的效果差异.方法 选取信阳市中心医院 62 例早期乳腺癌的患者.按照手术方式的不同分为整形组(采用整形保乳术)30 例和常规组(采用常规保乳术)32 例,比较两组围术期相关指标,术前、术后 3 个月的血清肿瘤标志物,美容效果,并发症发生情况以及 1 年生存率.结果 整形组手术时间、肿瘤与切缘最小距离长于常规组(P<0.05),整形组切除组织与乳房体积比大于常规组(P<0.05),整形组术中出血量、术后引流量少于常规组(P<0.05),整形组拔除引流管时间、住院时间短于常规组(P<0.05).术后 3 个月,两组血清VECF、TPS、CA125 较术前均降低,但整形组与常规组比较,差异无统计学意义(P>0.05).整形组美容优良率高于常规组(χ2 =4.737,P<0.05),并发症发生率低于常规组(χ2 =4.885,P<0.05).Kaplan-Meier曲线分析显示,整形组 29 例生存,生存率为 96.67%,常规组 31 例生存,生存率为 96.87%,两组生存率比较,差异无统计学意义(χ2= 0.001,P=0.973).结论 与常规保乳术相比较,整形保乳术应用于早期乳腺癌,可提高美容效果,降低并发症发生率,促进患者快速恢复.
Comparison of Cosmetic Effect and Survival Prognosis Between Plastic Breast Conserving Surgery and Conventional Breast Conserving Surgery in Early Breast Cancer Patients
Objective To compare the differences in effectiveness between plastic breast con-serving surgery and conventional breast conserving surgery.Methods 62 patients diagnosed with early breast cancer were selected from Xinyang Central Hospital.According to the different sur-gical methods,30 cases were divided into the plastic surgery group(using plastic breast con-serving surgery)and 32 cases were divided into the conventional group(using conventional breast conserving surgery).The perioperative related indicators,serum tumor markers before and 3 months after surgery,cosmetic effects,incidence of complications,and one-year survival rate were compared between the two groups.Result Compared with the conventional group,the plastic surgery group had significantly longer surgical time,minimum distance between tumor and cutting edge(P<0.05),significantly higher resection tissue/breast volume ratio(P<0.05),significantly less intraoperative bleeding and postoperative drainage volume(P<0.05),and significantly shorter drainage tube removal time and hospital stay(P<0.05).Three months after surgery,the serum VECF,TPS,and CA125 levels in both groups decreased compared to before surgery,but there was no statistically significant difference between the plastic surgery group and the conventional group(P>0.05).The excellent and good cosmetic rate in the plastic surgery group was 96.67%,which was significantly higher than 78.13%in the conventional group(P<0.05).The incidence of complications in the plastic surgery group was 6.67%,which was significantly lower than the 28.13%in the conventional group(P<0.05).Kaplan Meier curve analysis showed that 29 patients in the plastic surgery group survived with a survival rate of 96.67%,while 31 patients in the conventional group survived with a survival rate of 96.87%.There was no statistically significant difference in the survival rates between the two groups(χ2 =0.001,P= 0.973).Conclusion Compared with conventional breast conserving surgery,plastic breast conserving surgery applied to early breast cancer can improve the cosmetic effect,re-duce complications and promote rapid recovery of patients.

Breast cancerBreast conserving surgeryPlastic surgeryBeautyprognosis

丁皓、吴祥虎、陈春龙

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信阳市中心医院肿瘤外科一病区(河南 信阳 464000)

乳腺癌 保乳术 整形 美容 预后

2024

湖北民族大学学报(医学版)

湖北民族大学学报(医学版)

ISSN:
年,卷(期):2024.41(1)
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