Analysis of Medication Rules for the Treatment of Irregular Menstruation in Chen Su'an's Gynecological Remedies:Menstrual Regulation
Objective To summarize and analyze the medication rules of Chen Su'an's Gyneco-logical Remedies:Menstrual Regulation.Methods The formulas included in Chen Su'an's Gyne-cological Remedies:Menstrual Regulation were organized and a database was established using Excel 2010 software.SPSS Modeler 18.0 and SPSS Statistics 25.0 software were used for data analysis of the medicinal ingredients in the traditional Chinese medicine prescriptions.Results A total of 54 formulas were included,involving 115 different medicinal ingredients,with a cumula-tive frequency of medication use reaching 630 times.Statistical analysis revealed that the most frequently used medicinal ingredients were Danggui,Chuanxiong,Xiangfu,Mudanpi,and Sheng-dihuang.In the high-frequency medicinal ingredients(used frequency≥10 times),the most frequently used medicinal properties were warm,and the most frequently used tastes were sweet and bitter.The most frequently associated meridians were Liver,Spleen,and Heart.The top three association rules were Danggui-Chuanxiong,Xiangfu-Danggui,and Baishao-Chuanx-iong.Cluster analysis of high-frequency medicinal ingredients revealed four combination groups.In the decision tree model analysis,Danggui served as the dependent variable,and Chuanxiong,Chishao,Fuling,and Honghua were found to have an important position in medication compati-bility,with Chuanxiong being the best identifying medicinal ingredient.Conclusion Chen Su'an believes that various ailments in women are all caused by menstrual irregularities.The pathology of these diseases primarily lies in the liver and spleen,manifesting as stagnant Qi and deficient blood.He highlights the efficacy of Siwutang in nourishing blood and promoting blood circula-tion,Sijunzitang in supplementing Qi and strengthening the spleen,as well as the role of Xi-aoyaosan in soothing the liver and regulating Qi.He also emphasizes that in the regulation of menstruation,it is important to nourish both blood and Qi,with a primary focus on nourishing blood and promoting blood circulation.Additionally,he suggests sweet and warm herbs to strengthen the spleen and facilitate nourishment,while maintaining a balance between cold and warm properties for overall harmony.
data miningChen Su'an's gynecological remediesmenstrual regulationmedi-cation rules