A Controlled Study on the Association of Risk Factors for Cerebral Infarction and Cerebral Hemorrhage
Objective To explore the differences and associations between the risk factors of cerebral infarction(CI)and cerebral haemorrhage(CH).Methods Patients with CI or CH who attended the Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine from January 2019 to December 2022 were selected,and a 1∶1 individually matched case-control study design was used(every 1 patient with CI was matched with a CH patient of his/her gen-der and age),with a total of 300 study subjects in 150 paired groups.At the same time,80 healthy individuals who underwent routine medical check-ups at our medical check-up centre were selected as the healthy control group(HC group).General demographic data,past medi-cal history and behavioural factors of the study subjects were collected and serological test re-sults were obtained using standardized methods.Results The abnormal rates of history of heart disease and D-D were higher in the CI group than those in the CH group,and the abnormal rates of history of smoking,drinking and hypertension were lower than those in the CH group(P<0.05).The levels of LP(a),TC,TG,LDL,Hcy,UA,FIB,D-D,APTT,TT,NEUT,and MPV were compared among the three groups,with statistically significant differences(P<0.05).The levels of LP(a),TC,TG,LDL,Hcy,UA,FIB,D-D,APTT,TT,NEUT,and MPV levels were higher than those in the HC group(P<0.05).LP(a),TC,TG,LDL,Hcy,UA,FIB,D-D,APTT,TT,NEUT,and MPV levels in the CH group were higher than those in the HC group(P<0.05);The levels of LP(a),FIB,and D-D in the CI group were higher than those in the CH group(P<0.05).Con-clusion Most of the risk factors of CI and CH were the same,but there were significant differ-ences in LP(a),FIB,D-D,history of heart disease,history of smoking,history of alcohol con-sumption and history of hypertension,and D-D had a greater effect on CI.
cerebral infarctioncerebral hemorrhagerisk factorsassociationcontrolled study