Objective To observe the effect of negative pressure drainage on cervical tuberculous lymphadenitis(CLT)and to analyze the influencing factors for its recurrence.Methods A total of 152 CTL patients treated in Hebei Chest Hospital were selected as the research objects,and they were divided into experimental group(n=100)and control group(n =52)according to postoperative drainage mode.Negative pressure drainage and conventional drainage were performed in the experimental group and control group,respectively.Postoperative drainage volume,postoperative drainage time,length of stay,times of dressing changes,incidence of poor incision healing,postoperative recurrence rate and other indicators were compared between groups.Then,152 CTL patients were subdivided into recurrence group(n=23)and non-recurrence group(n=129).The clinical data of the two groups were compared,and the risk factors for CTL recurrence were analyzed by COX regression.Results Compared with those of the control group,patients in the experimental group presented significantly higher postoperative drainage volume,shorter postoperative drainage time and length of stay,less times of dressing changes,and lower incidence of poor incision healing and postoperative recurrence rate than those of the control group(P<0.05).The postoperative recurrence of CTL was significantly correlated with the nutritional status,postoperative drainage mode,degree of lymph node dissection,and drug-resistant tuberculosis(P<0.05).Multivariate Cox analysis showed that postoperative drainage mode,degree of lymph node dissection and drug-resistant tuberculosis were independent risk factors for postoperative recurrence of CTL(P<0.05).Conclusion Negative pressure drainage is more suitable for postoperative drainage in CTL patients.Negative pressure drainage,thorough lymph node dissection and rational treatment of drug-resistant tuberculosis are beneficial to reduce the recurrent rate of CTL.