Analysis of residual stenosis of target vessels in patients with intracranial large artery occlusion and cerebral infarction after mechanical thrombectomy and the influencing factors
Objective To investigate the residual stenosis of target blood vessels in patients with cerebral infarction caused by intracranial large artery occlusion after mechanical thrombectomy and its influencing factors.Methods Clinical data of 102 patients with intracranial large artery occlusion and cerebral infarction who underwent mechanical thrombectomy in the hospital from January 2020 to December 2022 were retrospectively analyzed.According to the presence and absence of residual stenosis in the target vessel immediately after thrombectomy,patients were divided into residual stenosis group(n= 49)and non-residual stenosis group(n=53).The baseline data of patients were collected,and the relevant factors affecting the residual stenosis of target vessels after mechanical thrombectomy in patients with intracranial large artery occlusion and cerebral infarction were analyzed by the binary Logistic regression.Results Compared with those of non-residual stenosis group,patients in the residual stenosis group presented a significantly higher proportion of history of hypertension,diabetes and hyperlipidemia,higher preoperative levels of homocysteine(Hcy)and fibrinogen(FIB)and shorter preoperative prothrombin time(PT)(P<0.05).The binary Logistic regression analysis showed that history of hypertension,history of diabetes,history of hyperlipidemia,Hcy,FIB were risk factors for residual stenosis of target vessels after mechanical thrombectomy in patients with cerebral infarction due to intracranial large artery occlusion(OR>1,P<0.05),and PT was the protective factor(OR<1,P<0.05).Conclusion History of hypertension,diabetes and hyperlipidemia,preoperative Hcy,preoperative FIB and PT are the influencing factors for residual stenosis of target vessels after mechanical thrombectomy in patients with cerebral infarction caused by intracranial large artery occlusion.
intracranial large artery occlusioncerebral infarctionmechanical thrombectomyresidual stenosisinfluence factor