Objective To investigate the distribution characteristics of pathogenic microorganisms in elderly bedridden patients with pulmonary infection and to analyze the drug resistance,thus providing evidence for the rational use of antibacterial agents.Methods The clinical data of 236 cases of elderly bedridden patients with pulmonary infection treated in our hospital during the period from January 2019 to January 2022 were retrospectively analyzed.All patients underwent sputum bacterial culture,strain identification and drug sensitivity test.Results A total of 198 strains of pathogenic microorganisms were isolated from 236 elderly bedridden patients with pulmonary infection,most of which were Gram-negative bacteria(73.74%).The top five strains were the Acinetobacter Bauman,Pseudomonas aeruginosa,Klebsiella pneumoniae,Escherichia coli,and Staphylococcus aureus.The drug sensitivity test results indicated that 57.14%and 54.76%of Acinetobacter Bauman strains were resistant to imipenem and meropenem,respectively.The resistance rates of Pseudomonas aeruginosa strains to imipenem and meropenem were 33.33%and 30.00%,respectively.The resistance rates of Klebsiella pneumoniae strains to imipenem and meropenem were both 10.71%.Escherichia coli strains were highly sensitive to carbapenems,with the drug resistance rate of 0.A total of 57.14%of Staphylococcus aureus strains were resistant to methicillin.Vancomycin-resistant strains were not detected.Conclusion The pathogenic microorganisms distribution in elderly bedridden patients with pulmonary infection are mainly Gram-negative bacteria,and drug resistance is a serious event in major pathogenic microorganisms.Therefore,rational use of antibacterial agents relies on drug sensitivity testing.
万方数据
维普
