Effect of endometrial receptivity ultrasonic indicators on the outcome of frozen-thawed embryo transfer
Objective To study the effect of endometrial receptivity ultrasonic indicators on the pregnancy outcome of frozen-thawed embryo transfer(FET).Methods A total of 212 patients who underwent FET in our department were selected.The endometrial thickness and classification,the pulsatility index(PI),resistance index(RI),the ratio of peak systolic velocity to end diastolic velocity(S/D)of the uterine artery blood on day 3 of endometrium transformation,as well as the endometrial and sub-endometrial blood flow perfusion were measured by color Doppler ultrasound.The correlation of each index with the pregnancy outcome was analyzed.Results There were no significant differences in the endometrial thickness and uterine artery blood flow parameters between pregnancy group and non-pregnancy group(P>0.05).There was no significant difference in the rate of pregnancy between patients with bilateral or unilateral loss of diastolic blood flow in the uterine artery who were treated with the Low Molecular Weight Heparin Calcium and Tadalafil and those with the loss of diastolic blood flow(P>0.05).There were significant differences in the rate of clinical pregnancy and endometrial thickness among three types of endometrial and sub-endometrial blood flow(P<0.05).The endometrial thickness increased gradually from typeⅠ to typeⅢ group([9.017±1.203]mm,[9.339±1.758]mm,[10.520±1.938]mm).The pregnancy rates of typeⅡand typeⅢgroup(62.7％ and 60.9％)were significantly higher than that of typeⅠ group(25.0％).Conclusion The type of endometrial and sub-endometrial blood flow can predict outcome of FET,but endometrial thickness and uterine artery blood flow parameters alone have no predictive value.
万方数据
维普
