Objective To analyze the coincidence rate between gastroscopy and pathologic diagnosis in chronic atrophic gastritis,and explore pathological characteristics of different degree of atrophy and different age groups.Methods From June 2020 to August 2021,the basic data,gastroscopy and pathological reports,Helicobacter pylori infection data were collected form recruited 534 patients with suspected chronic atrophic gastritis diagnosed by gastroscopy.Results A total of 370 patients with chronic atrophic gastritis were diagnosed by pathology,and the coincidence rate between gastroscopy and pathologic diagnosis was 69.29%.Chronic atrophic gastritis was more common in the elderly,and there was no significant difference between men and women(P>0.05).The infection rate of Helicobacter pylori in chronic atrophic gastritis group was 45.95%,which was significantly different from that of chronic non-atrophic gastritis(P<0.05).The detection rates of atrophy,intestinal metaplasia and low-grade intraepithelial neoplasia of gastric antrum were higher than those of gastric angle,gastric body and other sites.The detection rates of high-grade intraepithelial neoplasia in the gastric fundus and gastric cardial were higher.The degree of atrophy in the chronic atrophic gastritis group was closely related to the degrees of intestinal neoplasia and intraepithelial neoplasia.The incidences of severe intestinal neoplasia and intraepithelial neoplasia were higher in the severe atrophy group than those in the mild and moderate atrophy groups.The incidences of enteralization and intraepithelial neoplasia in the elderly were the highest among different age groups(P<0.05).Conclusion For patients with chronic atrophic gastritis,the coincidence rate between gastroscopy and pathologic diagnosis is low.Gastric antrum is prone to atrophy and intestinal metaplasia.The incidences of intestinal metaplasia and intraepithelial neoplasia are positively related with atrophy.The incidence of atrophy,intestinal metaplasia and intraepithelial neoplasia in the elderly are the highest.
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