Clinical efficacy of intramuscular injection of Cobamamide,water-filtered infrared A irradiation combined with plum-blossom needle for acute herpes zoster
Objective To explore the effectiveness and superiority of intramuscular injection of Cobamamide,water-filtered infrared A(wIRA)irradiation combined with plum-blossom needle(PBN)for acute herpes zoster(AHZ).Methods From September 2020 to May 2022,totally 124 AHZ patients diagnosed in the Department of Dermatology of our hospital were randomly divided into the control group and the observation group.All patients were managed by Western medicine treatment(intramuscular injection of Cobamamide,oral valacyclovir and vitamin B1,supplemented with wIRA irradiation),and those in the observation group were additionally treated with PBN acupuncture and fire cupping therapy.The therapeutic outcomes,pain relief time,and the incidence of postherpetic neuralgia were compared between groups.The clinical effectiveness in the observation group was comprehensively assessed.Results The difference was not statistically significant in age and course of disease between groups(P>0.05).The curative effect in the observation group was significantly better than that of the control group(χ2=8.904,P=0.031).The patients in the observation group presented significantly shorter pain relief time(t=3.402,P=0.001),and significantly lower incidence of postherpetic neuralgia(χ2 =4.835,P=0.028)than those of the control group.Conclusion For AHZ patients,intramuscular injection of Cobamamide,wIRA irradiation combined with PBN can improve treatment efficiency,significantly shorten pain relief time,and effectively reduce the incidence of postherpetic neuralgia.
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