Effects of body mass index changes during pregnancy on maternal and infant outcomes in pregnant women with gestational diabetes mellitus
Objective To investigate the correlation of body mass index(BMI)changes during pregnancy with maternal and infant outcomes in pregnant women with gestational diabetes mellitus(GDM).Methods Two hundred pregnant women with GDM who underwent pregnant examinations and delivered in Baise People's Hospital between 2019 and 2021 were selected as study subjects.According to the increase in the Body Mass Index(BMI)during pregnancy(ΔBMI),they were divided into insufficient BMI increase group(ΔBMI<4kg/m2,n= 51)and normal BMI increase group(4kg/m2≤ΔBMI≤6kg/m2,n = 87)and excessive BMI increase group(ΔBMI>6kg/m2,n = 62).Baseline information and experimental data of all subjects were obtained using questionnaire survey.The correlation of different BMI changes with maternal and infant outcomes was assessed using Logistic regression model analysis.Results The proportion of pregnancy-induced hypertension,preeclampsia and postpartum hemorrhage in the excessive BMI increase group was 29.03%,18.03%and 41.94%,respectively,which was 19.54%,14.94%,and 12.64%respectively in the normal BMI increase group,and 25.49%,7.84%and 13.73%respectively in the insufficient BMI increase group.The proportion of fetal distress and macrosomia in the excessive BMI increase group was 29.03%and 40.32%,respectively;which was 13.79%and 14.94%respectively in the normal BMI increase group,and 9.80%and 7.84%respectively in the insufficient BMI increase group.The incidence of postpartum complications and adverse neonatal outcomes in the excessive BMI increase group was significantly higher than that of normal BMI increase group and insufficient BMI increase group(P<0.05).With the indices in the normal BMI increase group as references,Logistic regression analysis showed that an insufficient increase in BMI during pregnancy significantly increased the risk of pregnancy-induced hypertension,preeclampsia,postpartum hemorrhage,fetal distress and macrosomia(OR=3.376,2.658,1.354,1.713 and 2.165,respectively;P<0.05).An excessive increase in BMI during pregnancy significantly increased the risk of pregnancy-induced hypertension,preeclampsia,postpartum hemorrhage,fetal distress,macrosomia,low birth weight infants and GDM(OR=2.647,1.659,3.675,4.132,2.876,3.151 and 3.325,respectively;P<0.05).Conclusion Either insufficient or excessive BMI increase in pregnant women with GDM would increase the incidence of adverse maternal and infant outcomes.Therefore,controlling the weight gain of monitorable pregnant women during pregnancy is not only beneficial to the health of the mothers and infants,but also has a positive impact on reducing the incidence of GDM and related complications.
gestational diabetes mellituspregnant womendifferent body mass index changes during pregnancymaternal and infant outcomescorrelation
万方数据
维普
