During the perioperative period,oxygen therapy is a routine respiratory support measure.However,the impact of the fraction of inspired oxygen(FiO2)at the varying concentrations differs a lot.The conventional theory of inhaling high concentrations of oxygen in reducing postoperative nausea and vomiting and preventing surgical site infections has gradually evolved.Oxygen is a potent oxidizing agent to trigger oxidative stress responses and oxidative damage in the lungs,thereby increasing the incidence of postoperative pulmonary complication(PPC).PPC can significantly increase early postoperative mortality,ICU admissions,and length of stay.Current research demonstrated a close correlation of the use of FiO2 at varying concentrations during perioperative mechanical ventilation with the occurrence of PPC.This review,by revisiting recent studies,explored the effects of FiO2 at varying concentrations on PPC,offering scientific evidences for perioperative oxygen management.The aim of this review was to decrease the risk of PPC and enhance the quality of postoperative recovery through more optimized perioperative oxygen management strategies.
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维普
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