缺铁性贫血合并焦虑抑郁的易感因素及发病机制研究进展
Research progress on susceptible factors and pathogenesis of iron deficiency anemia combined with anxiety and depression
赵婉婷 1陈涛 1常延博 2彭紫涵 2吕佳欣 2戚天凤 2郭冬玉 1肖欣宇 2王金环 3郝晶3
作者信息
- 1. 150040 哈尔滨市,黑龙江中医药大学研究生院
- 2. 黑龙江中医药大学第一临床医学院
- 3. 黑龙江中医药大学附属第一医院血液病科
- 折叠
摘要
缺铁性贫血与焦虑抑郁的合病常被血液临床工作者忽视,焦虑抑郁与缺铁性贫血的转归互相影响,降低患者生活质量,加重不良预后.缺铁性贫血与焦虑抑郁合病的易感因素多样、发病机制复杂,明确易感因素及发病机制,提高缺铁性贫血与焦虑抑郁合病的关注度及实施有效的干预措施,可有效改善临床治疗效果及预后转归.本文基于现有研究,旨在探讨缺铁性贫血合并焦虑抑郁的易感因素,并从神经递质、髓鞘蛋白、海马体的物质与结构等多个方面剖析其合病的发病机制.以期提升临床医生对IDA合并焦虑抑郁的认识,关注IDA患者伴发的精神症状,提高患者的生活质量及临床疗效,改善患者预后.
Abstract
The combination of iron deficiency anemia(IDA)with anxiety and depression is often neglected by physicians in the hematology department.The regression of anxiety,depression and IDA affect each other,reducing the quality of life of patients and aggravating the poor prognosis.The combination of IDA with anxiety and depression has various susceptible factors and complex pathogenesis.The identification of susceptible factors and pathogenesis,the improvement of the concern to the combination of IDA with anxiety and depression and the implementation of effective interventions greatly favor the clinical treatment and prognosis.Based on the existing studies,this paper aims to investigate the susceptible factors of IDA combined with anxiety and depression,and to analyze the pathogenesis of the combined disease from various aspects like neurotransmitters,myelin proteins,and substances and structures of hippocampus.Our findings are expected to improve clinicians'understanding of IDA combined with anxiety and depression,highlight the accompanying psychiatric symptoms,and improve the quality of life,clinical outcomes and the prognosis.
关键词
缺铁性贫血/焦虑抑郁/易感因素/发病机制/研究进展Key words
iron deficiency anemia/anxiety and depression/susceptibility factors/pathogenesis/research progress引用本文复制引用
基金项目
国家自然科学基金项目(81673968)
全国中医临床特色技术传承骨干人才项目(国中医药人教函[2019]36号)
黑龙江省中医药学会青年中医药科技创新项目(ZHY19-029)
黑龙江中医药大学创新人才基金(2018KCD04)
黑龙江中医药大学科研基金项目(2019MS14)
黑龙江中医药大学大学生科技创新实验项目(2021-14)
出版年
2024
NETL
NSTL
维普
万方数据