IL-22在消化系统疾病中的研究进展
Research progress of interleukin-22 in digestive system diseases
张梦婕 1隋华 1朱婧 1汤庆丰1
作者信息
- 1. 201803 上海市第一人民医院嘉定医院(上海市嘉定区江桥医院)
- 折叠
摘要
消化系统疾病是临床常见病、多发病,具有发病率高、病因复杂、病程反复的特点.白介素 22(IL-22)于2000 年被发现,目前已被确定在胃肠道、胰腺、肝脏等消化系统疾病中具有关键性作用.本综述通过阐述IL-22 在各类消化系统疾病中的作用及IL-22 参与消化道黏膜修复、与肠道微生物的关系,总结IL-22 在消化系统疾病中的研究进展.
Abstract
Digestive system disease is a common and frequently-occurring disease in clinical practice,which is characterized by high incidence,complex etiology and repeated course of disease.Interleukin-22(IL-22)was discovered in 2000 and has been identified to have a key role in digestive system diseases such as gastrointestinal tract,pancreas,and liver.This review summarizes the research progress of IL-22 in digestive system diseases by elaborating the role of IL-22 in various digestive system diseases and the relationship between IL-22 involved in digestive tract mucosal repair and intestinal microorganisms.
关键词
白介素-22/消化系统疾病/肠道微生物/黏膜修复Key words
interleukin-22/digestive system diseases/intestinal microorganisms/mucosal repair引用本文复制引用
基金项目
国家自然科学基金面上项目(82174459)
上海市嘉定区科委项目(JDKW-2021-0023)
上海市嘉定区科委项目(JDKW-2022-0025)
上海市嘉定区卫生健康委员会科研基金(青年)项目(2021-QN-04)
上海市嘉定区江桥医院科技计划科技创新专项()
国家自然科学基金培育项目(202139B)
出版年
2024
NETL
NSTL
万方数据