Construction of a prediction model for catheter-related bloodstream infection in intensive care unit patients and its validation
Objective To investigate the risk factors for catheter-related bloodstream infection(CRBSI)in intensive care unit(ICU)patients,and to construct a risk prediction model for the CRBSI.Methods A total of 402 ICU inpatients admitted to Guangdong Second Provincial General Hospital from February 2021 to February 2023 were collected in this study,of which 280 patients from February 2021 to September 2022 were allocated into the test group for construct a prediction model,and 122 patients from October 2022 to February 2023 in the validation group for external validation.Univariate and multivariate logistic regression were implemented to analyze the risk factors of CRBSI in ICU patients.A nomogram to predict CRBSI in ICU patients was constructed based on risk factors,and its accuracy was verified.Results CRBSI was detected in 15/280(5.4%)cases in the test group and 8/122(6.6%)cases in the validation group.There was no significant difference in the incidence of CRBSI between the two groups(χ2=0.227,P=0.634).The results of multivariate analysis in the test group showed that catheter retention time,catheter sliding/sliding out,white blood cells,and albumin were independent risk factors for CRBSI in ICU patients(all P＜0.05).The verification results from nomogram model showed that the C-index of test group and validation group was 0.904 and 0.877,respectively.The areas under the curve(AUC)of the test group and validation group was 0.845 and 0.822,respectively.Decision curve analysis showed that nomogram had a better clinical benefit in the test group and validation group.Conclusion A nomogram created based on the risk factors of CRBSI can predict the risk of CRBSI in ICU patients,which is helpful for medical staff take effective intervention measures.
intensive care unitcatheter related bloodstream infectionnomogramprediction model
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