Objective To analyze the features of tidal volume function in children with adenovirus pneumonia,and to guide the clinical assessment,treatment and prognosis prediction.Methods A total of 102 children with adenovirus pneumonia who were hospitalized in the First Department of Respiratory Medicine of Hebei Children's Hospital from January 2018 to December 2021 were enrolled.They were divided into severe pneumonia group(n=49)and non-severe pneumonia group(n=53)according to Guidelines for the management of community-acquired pneumonia in children formulated by the Respiratory Branch of Chinese Pediatric Society of Chinese Medical Association in 2013.Data of tidal volume function were collected and compared.Results The tidal function of children with adenovirus pneumonia was characterized by a faster respiratory rate(RR),decreased tidal volume per kilogram of body mass(VT/kg),faster expiratory flow,early appearance of peak tidal expiratory flow(PTEF),and declines of time at PTEF to total expiratory time(TPTEF/TE)and ratio of volume to peak expiratory flow and expiratory volume(VPEF/VE).The RR of the severe adenovirus pneumonia group was significantly faster than that of the non-severe adenovirus pneumonia group(P＜0.05).VT/kg,TPTEF/TE,VPEF/VE,and the tidal expiratory flow at 75%of the remaining tidal volume(TEF25)were significantly lower than those of the non-severe adenovirus pneumonia group(P＜0.05).The tidal breathing follow-volume(TBFV)curve of adenovirus pneumonia was mainly characterized by obstructive ventilatory dysfunction.The posterior part of the descending branch of the expiratory phase was inclined to the horizontal axis.The small airway obstruction in children with severe adenovirus pneumonia was more severe,and the slope of the middle and posterior part of the descending branch of the TBFV curve was too large,showing a tendency to sink toward the horizontal axis.Conclusion The lung function of children with adenovirus pneumonia is mainly manifested as small airway obstruction.In children with severe pneumonia,the small airway is more severely damaged,and it is easy to cause sequelae like bronchiolitis obliterans.Strengthening the management of small airway function in children with adenovirus pneumonia is the key event to reduce and prevent the respiratory sequelae.
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