Objective To explore the application of quantitative parameters of high-resolution magnetic resonance imaging(HR-MRI)and computed tomography perfusion(CTP)in patients with moyamoya disease.Methods The clinical data of 68 patients with moyamoya disease and 42 patients with cerebral atherosclerosis admitted from January 2020 to June 2023 were retrospectively analyzed.The quantitative parameters of HR-MRI in outer diameter,outer edge area and CTP of cerebral blood flow,cerebral blood volume,mean transit time,and peak time were compared between the two groups.The receiver operating characteristic(ROC)curve was drawn to analyze the diagnostic value of quantitative parameters of HR-MRI and CTP for moyamoya disease.The changes in quantitative parameters of CTP before and after revascularization in patients with moyamoya disease were compared.Results The outer diameter and outer edge area of blood vessels in patients with moyamoya disease were smaller than those of patients with cerebral atherosclerosis(P＜0.05).The cerebral blood flow of patients with moyamoya disease was significantly lower than that of patients with cerebral atherosclerosis,and the average transit time and peak time were significantly longer than those of patients with cerebral atherosclerosis(P＜0.05).The ROC curve showed that the outer diameter of blood vessels,the outer edge area of blood vessels,cerebral blood flow,mean transit time and peak time had certain diagnostic value for moyamoya disease(areas under curve[AUC]＞0.7,P＜0.05),and the outer edge area of blood vessels in HR-MRI and cerebral blood flow in CTP had the highest diagnostic value.After vascular reconstruction,the cerebral blood flow of patients with moyamoya disease was significantly higher than that before operation,and the mean transit time and peak time were significantly shorter than those before operation(P＜0.05).Conclusion The quantitative parameters of HR-MRI and CTP have certain characteristics in the diagnosis of moyamoya disease,which can improve the accuracy of differentiation.In addition,quantitative parameters of CTP can also be used for clinical efficacy evaluation.
moyamoya diseasehigh-resolution magnetic resonance imagingcomputed tomography perfusion(CTP)
NETL
NSTL
万方数据
