Objective To explore the influencing factors of stress injury in patients undergoing radical cervical cancer surgery and to construct a risk model.Methods A total of 250 patients with cervical cancer undergoing radical surgery from January 2021 to January 2023 in the First Affiliated Hospital with Nanjing Medical University were retrospectively included.They were divided into stress injury group(21 cases)and non-stress injury group(229 cases)according to the presence or absence of a stress injury.The basic information and operation-related indicators on admission of the two groups were collected and compared.Logistic regression was used to analyze the influencing factors of stress injury in patients.According to the results of logistic regression analysis,a risk prediction model was constructed,and the receiver operating characteristic(ROC)curve was drawn to analyze the predictive efficacy of the risk model.Results Univariate analysis showed that there were significant differences in the history of diabetes,hypoproteinemia,serum high-sensitivity C-reactive protein(hs-CRP)and intraoperative hypothermia between the two groups(P＜0.05).Logistic regression analysis showed that the history of diabetes,hypoproteinemia,high serum hs-CRP level and intraoperative hypothermia were the influencing factors for stress injury in patients undergoing radical surgery for cervical cancer(P＜0.05).The risk prediction model was constructed and the ROC curve was drawn to verify the model internally.The results showed that the area under the curve(AUC)of the model to predict the occurrence of stress injury in patients undergoing radical surgery for cervical cancer was 0.846,and the specificity and sensitivity were 0.729 and 0.810,respectively.External validation showed that the AUC of the risk prediction model in predicting stress injury in cervical cancer patients undergoing radical surgery was 0.859,with the specificity and sensitivity of 0.764 and 0.810,respectively.Conclusion Diabetes history,hypoproteinemia,high serum hs-CRP level,and intraoperative hypothermia are the influencing factors of stress injury in cervical cancer patients undergoing radical surgery.The risk model based on the above factors has a good predictive value for stress injury.
cervical cancerstress injurydiabeteshypoproteinemiahigh-sensitivity C-reactive protein
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