河北医药2024,Vol.46Issue(11) :1652-1655,1660.DOI:10.3969/j.issn.1002-7386.2024.11.010

立体定向微创手术治疗少量丘脑出血的临床效果

Clinical effect of stereotactic minimally invasive surgery on thalamic hemorrhage with a small amount

吴晓赟 李京臣
河北医药2024,Vol.46Issue(11) :1652-1655,1660.DOI:10.3969/j.issn.1002-7386.2024.11.010

立体定向微创手术治疗少量丘脑出血的临床效果

Clinical effect of stereotactic minimally invasive surgery on thalamic hemorrhage with a small amount

吴晓赟 1李京臣2
扫码查看

作者信息

  • 1. 050051 石家庄市,河北医科大学第三医院老年病科
  • 2. 河北医科大学第二医院神经外科
  • 折叠

摘要

目的 探索立体定向微创手术治疗少量丘脑出血的临床效果.方法 回顾性分析 2019 年 10 月至2022 年 5 月收治的 110 例少量丘脑出血(出血量 6~15 mL)的患者.治疗组患者(55 例)采用立体定向微创手术治疗,对照组患者(55 例)采用保守治疗方法.使用美国国立卫生研究院卒中量表(NIHSS)、格拉斯哥昏迷评分(GCS)及扩充版格拉斯哥预后(GOS-E)评分对所有患者进行评估,比较 2 组患者入院时NIHSS评分、治疗后 2 周和治疗后 4周时NIHSS评分的变化,治疗前后血肿量、GOS-E评分的变化,并发症发生率以及出院 6 个月后,患者的NIHSS及GOS-E评分,并进行统计学分析.结果 治疗后2 周、4 周,治疗组NIHSS评分、GOS-E评分均优于对照组(P<0.05);治疗后 3d和 7 d,2 组血肿体积均小于入院时(P<0.05),且治疗组小于对照组(P<0.05);治疗组颅内感染发生率高于对照组(P<0.05),对照组脑积水、肺部感染及下肢血栓发生率高于治疗组(P<0.05);6 个月后复诊,治疗组患者NIHSS评分显著低于对照组(P<0.05),治疗组GOS-E评分高于对照组(P<0.05).结论 与保守治疗效果相比,立体定向微创手术可显著改善少量丘脑出血患者的转归和预后.

Abstract

Objective To explore the clinical effect of stereotactic minimally invasive surgery on the treatment of small amount of thalamic hemorrhage.Methods A retrospective analysis was performed on 110 patients with small amount of thalamic hemorrhage(hematoma volume 6-15mL)admitted to our hospital from October 2019 to May 2022.Stereotactic minimally invasive surgery and conservative treatment were performed in the treatment group(55 cases)and the control group(55 cases),respectively.All patients were evaluated using the National Institutes of Health Stroke Scale(NIHSS),Glasgow Coma Score(GCS),and the expanded Glasgow Prognosis(GOS-E)score.Changes in the NIHSS score at admission,2 weeks after treatment and 4 weeks after treatment were compared between the two groups.Changes in hematoma volume and GOS-E score before and after treatment were compared as well.The incidence of complications and the NIHSS and GOS-E scores at 6 months after discharge were also compared.Results The 2-week and 4-week NIHSS score and GOS-E score in the treatment group were significantly better than those of the control group(P<0.05).The 3-day and 7-day hematoma volume in the both groups were significantly smaller than those at admission(P<0.05),and which in the treatment group were significantly smaller than those of the control group(P<0.05).The incidence of intracranial infection in the treatment group was significantly higher than that of the control group(P<0.05).The incidence of hydrocephalus,pulmonary infection,and lower extremity thrombosis in the treatment group was significantly lower than that of the control group(P<0.05).After 6 months of follow-up,the NIHSS score in the treatment group was significantly lower than that of the control group(P<0.05),and the GOS-E score in the treatment group was significantly higher than that of the control group(P<0.05).Conclusion The stereotactic minimally invasive surgery can significantly improve the outcome and prognosis of patients with small amounts of thalamic hemorrhage compared to the conservative treatment.

关键词

丘脑出血/微创手术/立体定向/高血压脑出血

Key words

thalamic hemorrhage/minimally invasive surgery/stereotactic/hypertensive cerebral hemorrhage

引用本文复制引用

基金项目

河北省医学科学研究项目(20190636)

出版年

2024
河北医药
河北省医学情报研究所

河北医药

CSTPCD
影响因子:1.075
ISSN:1002-7386
参考文献量12
段落导航相关论文