Objective To explore the intervention effect of improved pre-hospital emergency procedures in patients with acute cerebral infarction(ACI).Methods From May 2021 to April 2022,eighty ACI patients admitted to Department of Emergency,Shanghai Tenth People's Hospital were randomly assigned to the control group(n=40)and the observation group(n=40),in which they received conventional pre-hospital emergency and improved model of pre-hospital emergency procedures,respectively.The intervention effects of the two groups were compared.Results After intervention,significantly decreased National Institutes of Health Stroke Scale(NIHSS)score,and significantly increased Barthel Index(BI)score were detected in the two groups(all P<0.05),and the observation group was superior to the control group for NIHSS and BI scores(all P<0.05).Time of prehospital care provided by emergency medical services(EMS),waiting for triage,transfer time and time from onset to surgery in the observation group were all significantly shorter than those of the control group(P<0.05).The rescue effectiveness of the observation group was significantly higher than that of the control group(P<0.05).The prognostic outcome of the observation group was better than that of the control group(P<0.05).The satisfaction score of prehospital care provided by EMS was significantly higher in the observation group than that of the control group(P<0.05).Conclusion For ACI patients,improved model of pre-hospital emergency procedures can effectively improve neurological function,shorten pre-hospital time,and improve quality of life,rescue efficiency,and prognostic effect,especially of increasing pre-hospital emergency satisfaction.