Exosomes are nanoscale membranous vesicles actively secreted by a variety of cells in physiological and pathological states,which play an important role in signal exchange and substance transfer between cells.They greatly influence the occurrence and development of many diseases.Epstein-Barr virus(EBV)is a kind of human lymphocytic double-stranded DNA herpes virus,which is generally susceptible to human population.Studies have shown that exosomes secreted by EBV-infected cells play a key role in the occurrence,development and outcome of EBV infection-associated diseases.In recent years,with the deepening understanding of the molecular information contained in EBV-associated exosomes and their functions,their role in disease progression has been greatly concerned.This paper mainly reviewed the mechanism of exosomes in EBV-related neoplastic diseases,so as to enrich the pathogenesis of EBV-related neoplastic diseases and explore the application of exosomes in the diagnosis and treatment of EBV-related neoplastic diseases.
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