Follow-up study of neurodevelopment of low birth weight infants with varying risk grades by general movements assessments
Objective To analyze the effect of early rehabilitation interventions based on the risk grades of general movements(GMs)assessment on the neurodevelopment of low birth weight infants with corrected age of 6 and 12 months,thus providing references for formulating clinical management and rehabilitation plans.Methods A total of 150 low birth weight infants who received GMs in the department of neonatology and re-examined in outpatient clinic after discharge.According to the two rounds of evaluation results,the premature babies were assigned into high-risk group(grade Ⅰ),moderate-risk group(grade Ⅱ)and low-risk group(grade Ⅲ).They were managed by early rehabilitation interventions based on the risk grades of GMs.Neurodevelopmental results at the corrected age of 6 and 12 months,and neurodevelopmental outcome at the corrected age of 12 months were compared among the three groups.Results At the corrected age of 6 months,there were significant differences in developmental quotient scores of fine motor,social adaptation,language,and personal social behavior among the three groups(P<0.05).At the corrected age of 12 months,there were significant differences in the scores of five domains among the three groups(P<0.01).At the corrected age of 12 months,9 cases had abnormal neurodevelopmental outcome,including 1 case of cerebral palsy(high-risk grade Ⅰ)and 8 cases of motor development delay(high-risk grade Ⅰ in 2 cases,moderate-risk grade Ⅱ in 4 cases,low-risk grade Ⅲ in 2 cases).Conclusion Fined management guidance based on GMs at varying risk grades can promote the neurological development of low birth weight infants and reduce neurodevelopmental abnormalities,which can be further promoted and applied in clinical work.
general movementslow birth weight infantearly interventionneurodevelopment