择期外科手术患者焦虑抑郁情绪的危险因素及对应激反应的影响
Risk factors and effects of anxiety and depression in patients with elective surgery
刘畅 1王娇 1张丽玲 1安媛1
作者信息
摘要
目的 探讨择期手术患者焦虑抑郁情绪相关危险因素及焦虑抑郁情绪对手术患者应激反应的影响.方法 对接受择期外科手术患者100例,采用焦虑自评量表及抑郁自评量表调查进行问卷调查,以问卷得分为标准,术前发生焦虑或抑郁情绪患者作为观察组,未发生焦虑、抑郁患者作为对照组,比较2组临床特征差异,对比2组手术患者术前、术后24 h患者血清超氧化物歧化酶活性、肾上腺素水平以及术后并发症发生情况.结果 2组患者术前、术后24 h超氧化物歧化酶活性及术前术后24 h肾上腺素水平对比差异均有统计学意义(P＜0.05).试验组术后1个月并发症发生率为30.95％,对照组为13.79％,2组并发症发生率差异有统计学意义(P＜0.05).Logistic逐步回归分析表明,男性、文化程度高、病程长、月收入低是择期手术患者发生焦虑、抑郁情绪的危险因素(P＜0.05).结论 男性、文化程度高、病程长、收入低为择期手术患者焦虑抑郁情绪的危险因素,焦虑抑郁情绪加重择期手术患者围手术期的应激反应,增加手术并发症的发生.
Abstract
Objective To explore the related risk factors of anxiety and depression in patients with elective surgery and their influence on patients'stress response.Methods One hundred patients with elective surgery were investigated with Self-rating Anxiety Scale(SAS)and Self-rating Depression Scale(SDS).According to SAS and SDS scores,the patients with anxiety or depression before surgery were taken as the observation group,and the patients without anxiety or depression as the control group.The clinical features,the serum superoxide dismutase(SOD)activity and epinephrine levels preoperatively and at 24 hours postoperatively,postoperative complications between the two groups were compared.Results There were statistically significant differences in serum superoxide dismutase(SOD)activity and epinephrine levels preoperatively and at 24 hours postoperatively between the two groups(P＜0.05).The stress response of patients in the observation group was more severe than that in the control group preoperatively and at 24 hours postoperatively.The incidence of complications at 1 month postoperatively in the observation group was higher than that in the control group(P＜0.05).Conclusion The risk factors for anxiety and depression in patients with elective surgery are male gender,high education level,long disease course,and low income.The anxiety and depression will aggravate the stress response of patients undergoing elective surgery and increase the incidence of complications.
关键词
焦虑/抑郁/择期手术/危险因素/并发症Key words
anxiety/depression/elective surgery/risk factor/complication引用本文复制引用
基金项目
河北省医学科学研究课题计划(20221696)
出版年
2024
NETL
NSTL
万方数据