Correlation analysis between platelet count and bone mineral density in the elderly
Objective To analyze the correlation between platelet count(PLT)and bone mineral density(BMD)in the elderly.Methods Clinical data of 1,861 elderly patients who underwent routine physical examination in our hospital from January 2017 to December 2020 were retrospectively analyzed.They were assigned into osteoporosis group(n=714)and non-osteoporosis group(n=1,147).PLT and BMD were compared between groups,and their correlation was assessed by Pearson correlation.The receiver operating characteristic(ROC)curve was drawn to analyze the predictive value of PLT and BMD in osteoporosis.Results There were no significant differences in gender,age,albumin(ALB),blood glucose(GLU),creatinine(CREA),urea nitrogen,glycated hemoglobin(HbA1c),total serum protein(TP),red blood cell count(RBC)and hemoglobin(HGB)between osteoporosis group and non-osteoporosis group(P＞0.05).Pearson correlation analysis showed that PLT had a negative correlation with BMD(r＜0.05,P＜0.05).The ROC curve was drawn,and the results showed that the area under the curve(AUC)of PLT,BMD and their combination in discriminating osteoporosis was 0.777(0.757-0.798),0.828(0.807～0.849)and 0.835(0.817～0.852),respectively,presenting a certain predictive value.Conclusion Platelet count has a negative correlation with bone mineral density,both of which have certain predictive value for osteoporosis.Their combination detection is more effective in the diagnosis of osteoporosis.
platelet countbone mineral densityelderlyosteoporosis
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NSTL
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