Therapeutic effect of tamsulosin combined with escitalopram in the treatment of chronic pelvic pain syndrome
Objective To comprehensively analyze the clinical efficacy,symptom improvement and inflammation level of tamsulosin combined with escitalopram in the treatment of chronic pelvic pain syndrome(CPPS).Methods A total of 120 patients with CPPS admitted to our hospital from January 2022 to January 2023 were enrolled and divided into control group(n=60)and observation group(n=60)by a random number table.All patients were treated with tamsulosin,those in the observation group were additionally treated with escitalopram.A 2-months of treatment was performed,aiming to compare urination symptoms,inflammatory factor levels,clinical indicators,symptom scores,and incidence of adverse reactions between groups before and after treatment.Results After treatment,the dimension scores and total scores of urinary frequency,urgency,dripping or a stream of urine,urination-induced pain score of the observation group were significantly lower than those of the control group(P＜O.05).The cure rate of the observation group was significantly higher than that of the control group(P＜0.05).The levels of white blood cell count(WBC),interleukin-1 beta(IL-1beta),interferon(INF)-alpha of the observation group were significantly lower than the control group,while the average urinary flow rate(AFR)and interleukin-2(IL-2)were significantly higher(P＜0.05).The incidence of adverse reactions in the observation group was comparable to the control group(P＞0.05).Conclusion Tamsulosin combined with escitalopram in the treatment of chronic pelvic pain syndrome is helpful to improve clinical symptoms and clinical indicators,inhibit inflammatory reaction,and has a good clinical efficacy.
NETL
NSTL
万方数据
