Clinical study on Chaizhu Jiangzhi capsule in the treatment of coronary borderline lesions with intermingled phlegm-stasis blood syndrome
Objective To study the clinical effect of Chaizhu Jiangzhi capsule in the treatment of coronary borderline lesions with intermingled phlegm-stasis blood syndrome.Methods Eighty patients with coronary borderline lesions of intermingled phlegm-stasis blood syndrome,who underwent coronary CT angiography(CTA)and diagnosed in our hospital from November 2021 to November 2023,were enrolled.The patients were divided into control group(n=40)and treatment group(n=40).All patients were given basic treatment,those in the treatment group were additionally given Chaizhu Jiangzhi capsule.After 6 months of treatment,the plaque-related indicators,blood lipid level and inflammatory indicators,traditional Chinese medicine(TCM)efficacy scores,syndrome scores,and Seattle Angina Questionnaire(SAQ)scores were compared between the two groups.Results The degree of area stenosis and diameter stenosis in treatment group was significantly lower than control group(P＜0.05).The levels of total cholesterol(TC),triglycerides(TG),low-density lipoprotein(LDL),very low-density lipoprotein(VLDL),high-sensitivity C-reactive protein(Hs-CRP)in treatment group were significantly lower that those of the control group,but high-density lipoprotein(HDL)level was significantly higher(P＜0.05).The efficacy score and syndrome scores of TCM were significant difference between the treatment group and the control group(P＜0.05).The scores of SAQ(physical limitation[PL],angina stability[AS],angina frequency[AF],treatment satisfaction[TS]and disease perception[DP])in treatment group were significantly higher than control group(P＜0.05).Conclusion The clinical effect of Chaizhu Jiangzhi capsule in the treatment of coronary borderline lesions with intermingled phlegm-stasis blood syndrome is better,which can significantly improve the coronary artery stenosis and clinical symptoms of patients,and effectively reduce the blood lipid level,which is worth popularizing.
万方数据
维普
