Objective To explore the application effect of an integrated model based on three-dimensional(3D)quality structure in endoscopic instruments of the disinfection supply center.Methods It was a retrospective analysis conducted between January 2022 and August 2023.According to endoscopy equipment treatment methods,endoscopic instruments with a conventional management from January 2022 to October 2022 were taken into the control group,and those managed by an integrated model based on 3D quality structure from November 2022 to August 2023 were collected into the observation group.The data were reviewed to compare the qualification of endoscopic instruments,occurrence of adverse events in endoscopic instrument management,quality of work and satisfaction of endoscopic instrument treatment between the two groups.Results Compared with those of the control group,the qualified rates of recycling,cleaning,disinfection,packaging and sterilization in the observation group were significantly higher(P<0.05).The incidence of adverse events in the management of endoscopic instruments in the observation group was significantly lower than that of the control group(P<0.05).The total score and the score of each dimension of work quality in the observation group were significantly higher than those of the control group(P<0.05).The satisfaction with the management methods of endoscopic instruments in the observation group was significantly higher than that of control group(P<0.05).Conclusion An integrated model based on 3D quality structure in endoscopic instruments of the disinfection supply center can effectively improve the qualification rate and work quality of endoscopic instruments,reduce the incidence of adverse events in the management of endoscopic instruments,and improve the satisfaction of staff.