首页|2型糖尿病合并泌尿系感染联合预测模型的构建与验证

2型糖尿病合并泌尿系感染联合预测模型的构建与验证

扫码查看
目的 建立2型糖尿病合并泌尿系感染(urinary tract infection,UTI)的列线图预测模型,为早期诊断UTI提供依据.方法 回顾性分析310例2型糖尿病患者临床资料,将其分为训练集217例和验证集93例.单因素和多因素logistic回归分析2型糖尿病患者发生UTI的危险因素,构建基于危险因素的列线图模型,并验证其准确性和可靠性.结果 310例2型糖尿病患者发生UTI 63例,UTI发生率20.3%;训练集UTI 41例占18.9%,验证集UTI 22例占23.7%.多因素回归分析结果显示,体重指数、C反应蛋白、白蛋白、糖化血红蛋白是影响2型糖尿病患者发生UTI的独立危险因素(P<0.05).验证结果显示,列线图模型在训练集与验证集的C指数分别为0.971和0.917,AUC为0.816和0.788,特异度为80.28%和71.59%,敏感度为77.27%和75.61%.结论 利用危险因素构建的列线图模型可有效预测2型糖尿病患者UTI发生风险,帮助医护人员制订针对性管理方案.
Construction and verification of prediction nomogram model for urinary tract infection in patients with type 2 diabetes
Objective To construction prediction nomogram model for urinary tract infection(UTI)in patients with type 2 diabetes(T2D),thus providing reference for early diagnosis for UTI.Methods This was a retrospective study involving 310 T2D patients,the patients were allocated into the test group(n=217)and the validation group(n=93).Univariate and multivariate logistic regression analyses were implemented to analyze UTI risk factors,the nomogram for risk factors was constructed for verifying the accuracy and reliability.Results Among 310 T2D patients,there were 63(20.3%)occured UTI,with UTI incidence rate of 18.9%(41/217)in the test group and 23.7%(22/93)in the validation group.The results from multivariate regression analysis demonstrated that body mass index,C-reactive protein,albumin,glycated hemoglobin were risk factors for UTI in T2D patients(P<0.05).The verification results from prediction nomogram model showed that the C-index of test group and validation group were 0.971 and 0.917,with the area under the curve(AUC)of 0.816 and 0.788,the specificity of 80.28%and 71.59%,and the sensitivity of 77.27%and 75.61%,respectively.Conclusion A the prediction nomogram model based on the risk factors in T2D patients can predict the UTI risk,which is capable of helping medical staff to develop targeted management strategies.

type 2 diabetesurinary tract infectionrisk factornomogramprediction model

张金凤、武艳、郑光波

展开 >

050100 河北省石家庄市井陉矿区人民医院检验科

河北医科大学第一医院检验中心

050100 河北省石家庄市井陉矿区人民医院内科

2型糖尿病 泌尿系感染 危险因素 列线图 预测模型

石家庄市科技局项目

231200213

2024

河北医药
河北省医学情报研究所

河北医药

CSTPCD
影响因子:1.075
ISSN:1002-7386
年,卷(期):2024.46(18)
  • 9