Effect of ice physiological saline gargle combined with cluster oral intervention on oral mucositis and sleep quality in patients with radiotherapy for nasopharyngeal carcinoma
Objective To study the effect of ice physiological saline gargle combined with cluster oral intervention on oral mucositis and sleep quality in radiotherapy for nasopharyngeal carcinoma(NPC).Methods One hundred NPC patients with radiotherapy in our hospital from January 2021 to June 2021 were randomly assigned into study group(n=50,conventional care)and control group(n=50,conventional care+ice physiological saline gargle+cluster oral intervention).The aim was to compare incidence of oral mucositis,oral pain,sleep quality,mental status,self-efficacy.Results The total incidence of oral mucositis was significantly lower in the study group than in the control group(P<0.05).After intervention,significantly lower the scores of Numerical Rating Scale(NRS),Pittsburgh Sleep Quality Index(PSQI),Self-rating Anxiety Scale(SAS),Self-rating Depression Scale(SDS),and significantly higher General Self-Efficacy Scale(GSES)scores were found in the study group than those of the control group(all P<0.05).Conclusion For NPC patients underwent radiotherapy,ice physiological saline gargle combined with cluster oral intervention can reduce the occurrence of oral mucositis,improve sleep quality,oral pain and psychological status,and enhance self-efficacy.