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甲状旁腺识别策略在终末期肾脏病患者中的应用价值

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目的 建立终末期肾脏病行透析治疗患者的数据模型,评价甲状旁腺超声识别策略的诊断效能和可行性.方法 选取2021年1月至2021年6月行甲状旁腺超声检查的慢性肾脏病受试者43例,从中识别出疑似甲状旁腺共112枚.以超声引导下细针穿刺细胞学病理+洗脱液Tg+iPTH为诊断金标准,判断"甲状旁腺识别策略"的诊断效能.根据是否使用甲状旁腺识别策略分为试验组和对照组.比较2组判断结果的组内相关系数.结果 试验组iPTH 水平(2148.744±796.178)pg/mL,对照组 iPTH 水平(23.676±13.133)pg/ml,2 组比较差异有统计学意义(t=22.954,P<0.01).甲状旁腺识别策略法判断甲状旁腺的诊断准确率为92.857%,敏感度为93.421%,特异度为91.667%,曲线下面积0.925,阳性预测值为95.946%,阴性预测值为86.842%.试验组5名医生甲状旁腺识别结果的组内相关系数为0.814,对照组5名医生甲状旁腺识别结果的组内相关系数为0.568.结论 基于本模型,甲状旁腺超声识别策略有较高的诊断效能,该方法可使不同超声医师得出准确且一致的识别结果.
Application value of parathyroid recognition strategy in patients with end-stage renal disease
Objective To establish a mathematical model for end-stage renal disease(ESRD)patients undergoing dialysis,and to evaluate the diagnostic efficacy and feasibility of parathyroid ultrasound identification strategy.Methods A total of 43 subjects with chronic kidney disease who underwent parathyroid ultrasound from January 2021 to June 2021 were selected.A total of 112 suspected parathyroid glands were identified from the subjects.Ultrasound-guided fine needle aspiration cytology,eluent Tg and intact parathyroid hormone(iPTH)were used as the diagnostic gold standard to evaluate the diagnostic efficacy of the parathyroid identification strategy.Subjects were divided into the experimental group(using parathyroid recognition strategy)and control group(without parathyroid recognition strategy),and the intra-group correlation coefficients were compared.Results There was a significant difference in the iPTH level between the experimental group([2 148.744±796.178]pg/mL)and control group([23.676±13.133]pg/mL)(t=22.954,P<0.01).The accuracy,sensitivity,specificity,area under the curve(AUC),positive predictive value and negative predictive value of the parathyroid identification strategy were 92.857%,93.421%,91.667%,0.925,95.946%and 86.842%,respectively.The intra-group correlation coefficient of parathyroid recognition of 5 doctors was 0.814 in the experimental group,and 0.568 in the control group.Conclusion Based on this model,parathyroid ultrasound recognition strategy has a high diagnostic efficiency.Parathyroid recognition strategy can enable different ultrasound doctors to obtain accurate and consistent recognition results.

parathyroid glandchronic kidney diseaseparathyroid identification strategyultrasoundintact parathyroid hormone(iPTH)detection of eluent

于冬、曾玲、杨辉、温莉、张涛、张书晨

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056200 河北省邯郸市,华北医疗健康集团峰峰总医院超声科

056200 河北省邯郸市,华北医疗健康集团峰峰总医院骨科

河北省优抚医院功能科

河北省优抚医院放射科

江苏省盐城市第一人民医院

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甲状旁腺 慢性肾脏病 甲状旁腺识别策略 超声 洗脱液iPTH检测

2024

河北医药
河北省医学情报研究所

河北医药

CSTPCD
影响因子:1.075
ISSN:1002-7386
年,卷(期):2024.46(24)