Prediction value of NLR,PLR and PCT for infectious shock in patients with severe sepsis
Objective To study the prediction value of neutrophil-to-lymphocyte ratio(NLR),platelet-to-lymphocyte ratio(PLR),and procalcitonin(PCT)for infectious shock in patients with severe sepsis.Methods Ninety-six patients with severe sepsis admitted to our hospital between December 2019 and December 2022 were enrolled as research subjects.The patients were grouped into the control group(n=58)and the study group(n=38)based on the presence or absence of infectious shock.The predictive value of NLR,PLR,and PCT for infectious shock in patients with severe sepsis was analyzed.Results There was no difference in baseline data such as gender,age,oxygenation index,lactate and heart rate between the two groups(P>0.05).Patients in the study group had significantly higher scores of Sequential Organ Failure Assessment(SOFA)and the Acute Physiology and Chronic Health Evaluation Ⅱ(APACHE Ⅱ),and the levels of NLR,PCT and PLR relative to those in the control group(all P<0.05).Logistic regression analysis revealed that NLR,PCT,and PLR were independent risk factors affecting the development of infectious shock in patients with severe sepsis(P<0.05);among which,the PCT single index had a higher value in predicting the severity of sepsis patients;the combination of NLR,PCT,PLR had the highest sensitivity and specificity.Conclusion The combination of NLR,PLR and PCT has a high reference value for the prediction of infectious shock in patients with severe sepsis.