Role of RAS and RAB interacting protein 1 in tumors
RAS and RAB interacting protein 1(RIN1)is a RAS effector that transmits RAS activation signals through its own effectors including tyrosine protein kinase ABL and coordinates downstream signal transduction to regulate behaviors for various cellular,such as receptor endocytosis,cell adhesion,and cell migration.Research has shown that RIN1 plays an important role in the occurrence,development,invasion,and metastasis of various tumors.In this review,the latest progresses regarding RIN1 role in tumors are comprehensively summarized,thus providing mechanistic insights into the signal transduction of related pathways.
RAS and RAB interacting protein 1(RIN 1)gene expression regulationtumor
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