Effects of varying length of light therapy on psychiatric symptoms and cognitive functions of schizophrenia patients in the recovery phase
Objective To evaluate the clinical efficacy and safety of varying length of light therapy on schizophrenia in the recovery phase.Methods A total of 164 schizophrenia patients in the recovery phase were randomly divided into the experimental 1 group(43 cases),experimental 2 group(39 cases),experimental 3 group(37 cases)and control group(45 cases).The control group was given routine nursing,and other three groups were implemented with light therapy at varying length(30min,60min and 90min in the experimental 1,2 and 3 groups,respectively).The clinical efficacy was assessed by grading the Positive and Negative Syndrome Scale(PANSS)and MATRICS consensus cognitive battery(MCCB).Results After 1 month of treatment,the negative symptoms,general psychopathology dimension scores and total psychiatric scores in the experimental 1 group,experimental 2 group and experimental 3 group were significantly lower than those of the control group(P＜0.05).Meanwhile,the scores mentioned above in the experimental 2 group and experimental 3 group were significantly lower than those of the experimental 1 group(P＜0.05).The scores of dimensions of attention/alertness,information processing speed,working memory,reasoning and problem solving,and social cognition and the total cognitive score of the experimental 1,2 and 3 groups were significantly higher than those of the control group(P＜0.05),and they were significantly higher in the experimental 2 and 3 groups than the experimental 1 group(P＜0.05).Conclusion Light therapy for 60 minutes and 90 minutes are better than 30 minutes in improving the mental symptoms and cognitive functions of patients with schizophrenia in the recovery phase.However,the efficacy is comparable between 60 minutes and 90 minutes.Light therapy for 60 minutes is the optimal to treat schizophrenia in the recovery phase.
NETL
NSTL
万方数据
