Effect of the concept of the enhanced rehabilitation after surgery on perioperative stress response and postoperative rehabilitation of pancreatic cancer patients
Objective To analyze the effects of the concept of the enhanced rehabilitation after surgery(ERAS)on perioperative stress response and postoperative rehabilitation in pancreatic cancer patients.Methods A total of 80 surgically treated pancreatic cancer patients from January 2020 to December 2023 were selected.They were randomly assigned into the control group(n=40,routine nursing care)and observation group(n=40,ERAS-based nursing care)based on the computer random number table method.The perioperative stress response,preparatory grief,postoperative rehabilitation process and quality of life were compared between the two groups.Results Three days after surgery,cortisol(Cor),adrenocorticotropic hormone(ACTH),prostaglandin E2(PGE2),and neuropeptide Y(NPY)of the both groups were significantly higher than the preoperative values,which were significantly lower in the observation group than the control group(P<0.05).After nursing,the Preparatory Grief in Advanced Cancer(PGAC)score in the observation group was significantly lower than that of the control group[30.25±4.17]points vs[35.60±4.22]points,P<0.05).The postoperative infusion volume,first exhaust time,first eating time,first drinking time,first defecation time,first off-bed activity time and length of stay were significantly less in the observation group than those of control group(P<0.05).In the observation group,the Functional Assessment of Cancer Therapy General(FACT-G)score was significantly higher than that of the control group[78.95±17.34]points vs[67.81±17.49]points,P<0.05).Conclusion The application of ERAS-based nursing care for pancreatic cancer patients can achieve remarkable results,which alleviates perioperative stress response and preparatory grief,shortens the postoperative rehabilitation process and promotes the improvement of their quality of life.
concept of enhanced rehabilitation after surgerypancreatic cancer surgerystress responserehabilitation processquality of life