河北科技师范学院学报2024,Vol.38Issue(2) :52-58.DOI:10.3969/J.ISSN.1672-7983.2024.02.008

Box-Behnken设计-响应面法优化芦笋粉中黄酮的提取工艺

Optimization of Extraction Process of Flavonoids from Asparagus Powder with Box-Behnken Design-response Surface Method

张巍元 杨哲 王丁丁 闫鹏宇 陈正佳 孙梦影 孙昊雪 赵琰 刘艳平
河北科技师范学院学报2024,Vol.38Issue(2) :52-58.DOI:10.3969/J.ISSN.1672-7983.2024.02.008

Box-Behnken设计-响应面法优化芦笋粉中黄酮的提取工艺

Optimization of Extraction Process of Flavonoids from Asparagus Powder with Box-Behnken Design-response Surface Method

张巍元 1杨哲 1王丁丁 1闫鹏宇 1陈正佳 1孙梦影 1孙昊雪 1赵琰 1刘艳平1
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作者信息

  • 1. 河北科技师范学院化学工程学院,河北秦皇岛,066600
  • 折叠

摘要

采用低共熔溶剂法从芦笋粉末中提取黄酮,通过Box-Behnken设计-响应面法对提取工艺进行了优化.结果表明:低共熔溶剂氢键供体与受体的选择以及氢键供体和受体的比例,对黄酮的提取有较为显著的影响,其中氢键供体选择尿素,受体选择氯化胆碱,供体受体比例为1∶2对黄酮的提取效率最佳,此外提取工艺的3个因素,提取时间、提取温度、料液比对黄酮的提取效率也有一定的影响,其影响程度按照由大到小的次序为:料液比、提取时间、提取温度.提取芦笋粉中黄酮的最优条件为:料液比1∶2,提取时间2 h,提取温度50 ℃.此工艺条件下得到总黄酮提取率为25.99%,响应面模型预测值为21.63%.

Abstract

The eutectic solvent method was used to extract flavonoids from asparagus powder,and the extrac-tion process was optimized by the Box-Behnken design-response surface method.The results showed that the selection of hydrogen bond donor and acceptor and the ratio of hydrogen bond donor and acceptor of low eutec-tic solvent had a significant impact on the extraction of flavonoids,and the extraction efficiency of flavonoids was the best when urea was selected as hydrogen bond donor,choline chloride as acceptor,and the ratio of donor to acceptor was 1∶2.The optimal conditions for the extraction of flavonoids from asparagus powder were as follows:solid-liquid ratio of 1∶2,extraction time of 2 h,and extraction temperature of 50 ℃.Under the conditions of this process,the extraction rate of total flavonoids was 25.99%,and the predicted value of the response surface model was 21.63%.

关键词

黄酮/提取工艺/芦笋粉/Box-Behnken设计-响应面法

Key words

Flavonoids/extraction process/asparagus powder/Box-Behnken design-response surface method

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基金项目

国家自然科学基金项目(22108061)

河北省自然科学基金项目(B2022407009)

河北科技师范学院博士启动基金项目(2022YB022)

河北科技师范学院博士启动基金项目(2022YB023)

河北省高等学校科学技术研究项目(QN2023108)

出版年

2024
河北科技师范学院学报
河北科技师范学院

河北科技师范学院学报

影响因子:0.414
ISSN:1672-7983
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