摘要
目的:观察调补脾肾中药复方治疗原发性骨质疏松症(primary osteoporosis,POP)的临床疗效.方法:POP患者共计 60 例,采用随机数字表法随机分为对照组(30例)和治疗组(30例).对照组治疗方法为常规综合治疗,治疗组治疗方法为在对照组的基础上加用调补脾肾中药复方.比较 2 组患者的骨密度、血清碱性磷酸酶(ALP)、血红蛋白(Hb)、白蛋白(ALB)、血钙(Ca)、血磷(P)及临床疗效.结果:治疗组总有效率高于对照组(P＜0.05).治疗后,2 组的ALP水平均降低,治疗组低于对照组(P＜0.05),Hb、ALB水平及骨密度均提高,三个指标相比较治疗组高于对照组(P＜0.05).结论:POP用调补脾肾中药复方治疗效果明确,能有效调节ALP、Hb、ALB水平,提高骨密度.
Abstract
Objective:To observe the clinical efficacy of a traditional Chinese medicine(TCM)compound for regulating spleen and kidney in the treatment of primary osteoporosis(POP).Methods:A total of 60 patients with POP were randomly divided into a con-trol group(30 patients)and a treatment group(30 patients).The control group received conventional comprehensive treatment,while the treatment group received the same treatment as the control group with the addition of the TCM compound for regulating spleen and kidney.The bone mineral density(BMD),serum alkaline phosphatase(ALP),hemoglobin(Hb),albumin(ALB),serum calcium(Ca),serum phosphorus(P),and clinical efficacy were compared between the two groups.Results:The total effective rate in the treat-ment group was higher than that in the control group(P＜0.05).After treatment,the serum ALP levels decreased in both groups,with the treatment group showing a lower level than the control group(P＜0.05);Hb,ALB and BMD all increased in both groups,with the treatment group demonstrating higher levels in these three indicators compared to the control group(P＜0.05).Conclusion:The TCM compound for regulating spleen and kidney exhibits a clear therapeutic effect in the treatment of POP,effectively regulating serum ALP,Hb,and ALB levels,and improving BMD.
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