Clinical Observation on Self-designed Pelvic Inflammatory Disease Prescription Based on Dispersing Fire-stagnation Theory Combined with Antibiotics in Treatment of Pelvic Inflammatory Disease with Damp-Heat Stasis Syndrome
Objective:To investigate the efficacy and safety of a self-designed pelvic inflammatory disease prescription based on the theory of dispersing fire-stagnation combined with antibiotics in the treatment of pelvic inflammatory disease(PID)with damp-heat sta-sis syndrome.Methods:A total of 132 PID patients were randomly divided into a control group(66 patients treated with cefdinir and metronidazole)and a treatment group(66 patients treated with cefdinir,metronidazole,and the self-designed pelvic inflammatory dis-ease prescription).The control group received oral cefdinir capsules and metronidazole tablets,while the treatment group received the self-designed pelvic inflammatory disease prescription orally in addition to the control group's treatment.The course of treatment was 14 days for both groups.The effective rate,traditional Chinese medicine(TCM)syndrome score,visual analog scale(VAS)score for ab-dominal pain,levels of C-reactive protein(CRP)and interleukin-2(IL-2),pelvic fluid volume,pelvic mass diameter,and adverse re-actions during treatment were compared between the two groups before and after treatment.Results:Due to adverse reactions during medication,a total of 129 patients were ultimately included in the statistical analysis,with 64 in the control group and 65 in the treat-ment group.After treatment,the effective rate in the treatment group was 93.85%,which was higher than the 81.25%effective rate in the control group(P＜0.05).After treatment,the TCM syndrome score,VAS score for abdominal pain,CRP and IL-2 levels were all im-proved compared to those before treatment,with a reduction in pelvic fluid volume and pelvic mass diameter.The treatment group per-formed better than the control group in all these aspects(P＜0.05).During the treatment period,the incidence of adverse reactions in the treatment group was lower than that in the control group(P＜0.05).Conclusion:The self-designed pelvic inflammatory disease pre-scription based on the theory of dispersing fire-stagnation combined with antibiotics has good clinical efficacy in the treatment of PID with damp-heat stasis syndrome.It can improve patients'symptoms,CRP and IL-2 levels,pelvic fluid volume,and pelvic mass diameter,with high safety.
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