首页|硫酸沙丁胺醇物与丙卡特罗物治疗支气管哮喘患儿的对比研究

硫酸沙丁胺醇物与丙卡特罗物治疗支气管哮喘患儿的对比研究

扫码查看
目的 对比分析硫酸沙丁胺醇与丙卡特罗治疗支气管哮喘(BA)患儿的研究效果.方法 选取BA患儿 90 例,随机分为研究组(n=45)和常规组(n=45),常规组予以丙卡特罗治疗,研究组予以硫酸沙丁胺醇治疗.比较2 组临床疗效、肺功能[用力肺活量(FVC)、呼气流量峰值(PEF)、第 1s用力呼气量(FEV1)]、哮喘症状评分、症状(哮鸣音、呼吸困难、咳嗽)消失时间及不良反应发生率.结果 研究组总有效率 95.56%(43/45)较常规组 77.78%(35/45)高(P<0.05);治疗后,研究组FVC、PEF、FEV1 水平较常规组高(P<0.05);治疗后,研究组哮喘日间症状、哮喘夜间症状评分均较常规组低(P<0.05);研究组咳嗽、哮鸣音、呼吸困难消失天数均较常规组短(P<0.05);2 组不良反应发生率对比差异无统计学意义(P>0.05).结论 和丙卡特罗治疗相比,硫酸沙丁胺醇治疗BA患儿,可提高疗效,改善肺功能和临床症状,安全可靠.
A Comparative Study of Salbutamol Sulfate and Procaterol in the Treatment of Children with Bronchial Asthma
Objective To compare and analyze the research effect of salbutamol sulfate and procaterol in the treatment of children with bronchial asthma.Methods 90 cases of children with bronchial asthma were selected and divided into an experimental group(n=45)and a control group(n=45)according to the random number table method.The control group was given procaterol drugs treatment,and the experimental group was was given salbutamol sulfate drugs treatment.The clinical ef-ficacy,pulmonary function[forced vital capacity(FVC),peak expiratory flow(PEF),forced expiratory volume in the first second(FEV1)],asthma symptom score,symptom disappearance time(cough disappearance time,wheezing sound disappearance time,dyspnea disappearance time)and adverse reactions occurrence rate were compared between the two groups.Results The total effective rate of the experimental group 95.56%(43/45)was higher than that of the control group 77.78%(35/45)(P<0.05);Af-ter treatment,the levels of FVC,PEF and FEV1 in the experimental group were respectively higher than those in the control group(P<0.05);After treatment,the scores of asthma daytime symptoms and asthma nighttime symptoms in the experimental group were respectively lower than those in the control group(P<0.05);The cough disappearance time,wheezing disappearance time and dyspnea disappearance time in the experimental group were respectively shorter than those in the control group(P<0.05);There was no significant difference in the occurrence rate of adverse reactions between the two groups(P>0.05).Con-clusion Compared with the procaterol drugs treatment,salbutamol sulfate drugs treatment for children with the bronchial asthma can improve the curative effect,improve the pulmonary function and clinical symptoms.It is safe and reliable.

Bronchial asthmaSalbutamol sulfateProcaterolClinical efficacyPulmonary function

白小航、常振东、穆艳艳

展开 >

南阳市中心医院,河南 南阳 473000

支气管哮喘 硫酸沙丁胺醇 丙卡特罗 临床疗效 肺功能

2024

哈尔滨医药
哈尔滨市医学会

哈尔滨医药

影响因子:0.697
ISSN:1001-8131
年,卷(期):2024.44(1)
  • 15