首页|达格列净治疗心力衰竭的研究进展

达格列净治疗心力衰竭的研究进展

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心力衰竭是各种心血管疾病的最终阶段,临床上普遍以强心、利尿剂、扩血管配合交感神经抑制剂及肾素-血管紧张素-醛固酮系统抑制剂为治疗心衰的手段,并在一定程度上延缓心力衰竭的进展,但心力衰竭患者的再发率及死亡率仍很高.近年来随着治疗糖尿病药物—达格列净的广泛应用,我们发现它能使心力衰竭患者获益.达格列净在2021 年2月心力衰竭治疗适应证被获批,并广泛应用于临床.现对钠-葡萄糖共转运体-2抑制剂达格列净在心力衰竭领域的最新研究进展作一综述.
Dapagliflozin In The Treatment of Heart Failure
Heart failure is the final stage of various cardiovascular diseases.Cardiac stimulant,diuretic,vasodilators com-bined with sympathetic nerve inhibition and renin-angiotensin-aldosterone system inhibition are the means of clinical heart failure treating.To a certain extent,they delay the progression of heart failure.But the recurrence rate and mortality of heart failure patients are still very high.In recent years,with the widespread use of the diabetes drug-dapagliflozin,we have found that it can benefit patients with heart failure.Dapagliflozin was approved for the treatment of heart failure in February 2021 and has been widely used in clinical practice.A review of the latest research progress of the sodium glucose cotransporter-2 inhibitor dapagliflozin in the field of heart failure is presented.

DapagliflozinHeart Failuresodium-dependent glucose transporters 2 Inhibitor

肇启迪、黄幸涛

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哈尔滨医科大学附属第二医院,哈尔滨 黑龙江 150070

达格列净 心力衰竭 钠葡萄糖共转运体-2抑制剂

2024

哈尔滨医药
哈尔滨市医学会

哈尔滨医药

影响因子:0.697
ISSN:1001-8131
年,卷(期):2024.44(2)
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