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催产素与卡孕栓联合使用对顺产后产后出血的临床观察

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目的 探讨分析催产素与卡孕栓联合使用对顺产后产后出血的临床效果.方法 选取 120 例顺产后产后出血产妇分为对照 1 组、对照 2 组、实验组,对照 1 组仅给予催产素治疗,对照 2 组仅给予卡孕栓治疗,实验组给予催产素与卡孕栓联合治疗,比较三组产妇出血量、止血时间、止血效果、凝血因子水平、不良反应.结果 三组产妇产后出血量及止血时间差异有统计学意义(P<0.05),实验组产妇较对照1组、对照 2 组产妇产后出血量显著减少,止血时间显著缩短(P<0.05).三组产妇止血效果总有效率差异有统计学意义(P<0.05),实验组产妇止血效果总有效率为 97.50%较对照 1 组(65.00%)、对照 2 组(62.50%)显著提高(P<0.05).治疗前三组产妇凝血因子Ⅶ、FIB、PTT、PT及PLT水平无显著性差异(P>0.05),治疗后三组产妇凝血因子Ⅶ、FIB、PTT、PT及PLT水平均显著改善,且治疗后实验组产妇凝血因子Ⅶ、FIB、PTT、PT及PLT水平较对照 1 组、对照2组产妇改善更显著(P<0.05).实验组、对照 1 组、对照 2 组产妇服药期间不良反应发生率分别为 10.00%、20.00%、17.50%,差异无统计学意义(P>0.05).结论 催产素与卡孕栓联合治疗产妇顺产后产后出血起到协同机制的作用,相互补充效果显著,可改善产妇凝血功能,缩短止血时间,安全性好,值得推广.
Clinical Observation of the Combination of Oxytocin and Suppository for Pregnancy in Treating Postpartum Hemorrhage after Natural Delivery
Objective To investigate and analyze the clinical effect of combined use of oxytocin and pregnancy-suppos-itory on postpartum hemorrhage after natural delivery.Methods A total of 120 cases of postpartum postpartum hemorrhage were selected and divided into control group 1,control group 2 and experimental group.Control group 1 only received oxytocin treatment,control group 2 only received pregnancy suppository treatment,and the experimental group received combined treat-ment with oxytocin and pregnancy suppository.The amount of blood loss,hemostatic time,hemostatic effect,coagulation factor level before and after treatment and the occurrence of adverse reactions were compared among the three groups.Results Post-partum blood loss and hemostatic time were significantly different among the three groups(P<0.05).Postpartum blood loss and hemostatic time were significantly reduced in the experimental group compared with control group 1 and control group 2(P<0.05).The total effective rate of hemostatic effect was significantly different among the three groups(P<0.05).The total effective rate of hemostasis in the experimental group was 97.50%,which was significantly higher than that in control group 1(65.00%)and control group 2(62.50%)(P<0.05).There were no significant differences in the levels of coagulation factor Ⅶ,FIB,PTT,PT and PLT in the three groups before treatment(P>0.05).The levels of coagulation factor Ⅶ,FIB,PTT,PT and PLT in the three groups were significantly improved after treatment,and the levels of coagulation factor Ⅶ,FIB,PTT,PT and PLT in the ex-perimental group were more significantly improved than those in control group 1 and control group 2(P<0.05).The incidence of adverse reactions during medication in experimental group,control group 1 and control group 2 was 10.00%,20.00%and 17.50%,respectively,with no statistical significance(P>0.05).Conclusion The combination of oxytocin and pregnancy supposi-tory plays a synergistic role in the treatment of postpartum postpartum hemorrhage,with significant complementary effect,im-proving maternal coagulation function and shortening hemostasis time,good safety,worthy of promotion.

oxytocinpregnancy-suppositorySpontaneous laborpostpartum hemorrhage

张丝妮

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广州市中西医结合医院,广东 广州 510800

催产素 卡孕栓 顺产 产后出血

2024

哈尔滨医药
哈尔滨市医学会

哈尔滨医药

影响因子:0.697
ISSN:1001-8131
年,卷(期):2024.44(3)