Study on the Relationship between LDL-C,RC and the Occurrence of Cardiovascular Events in Elderly Patients with Essential Hypertension
Objective This study aims to explore the relationship between low-density lipoprotein cholesterol(LDL-C),residual cholesterol(RC)and cardiovascular events in elderly patients with essential hypertension.Methods 138 elderly essen-tial hypertension patients were divided into 32 cases and 106 cases according to the occurrence of adverse cardiovascular events.The general data,admission serum TC,HDL-C,LDL-C,RC level,and neurological function score(NHISS)were compared between the two groups,and the ROC curve was used to analyze the prediction value of the above index level of cardiovas-cular events in patients with essential hypertension.Results Comparison of disease duration,dietary habits,blood pressure level,hypertension grades Ⅱ-Ⅲ,family history of CAD in the incident and no incident group,The difference was statistically significant(P<0.05);High lipid levels TC,HDL-C,and RC in the incident group compared with patients in the naive group,LDL-C was lower than that in the untreated group,The difference was statistically significant(P<0.05);Higher left ventricular end diastolic internal diameter(LVDD),left ventricular systolic end internal diameter(LVSD)than the occurrence group,Low left ventricular ejection fraction(LVEF)than in the untreated group,The difference was statistically significant(P<0.05);Area under the ROC curve of serum lipid TC,HDL-C,LDL-C,and RC levels for predicting cardiovascular events in patients(Area Under Curve,AUC)were 0.693,0.694,0.754,and 0.769,respectively,Sensitivity was 68.75%,62.50%,78.12%,and 62.50%,re-spectively,Specific was 68.87%,73.58%,64.15%,88.68%,The difference was statistically significant(P<0.05).Conclusions TC,HDL-C,LDL-C and RC levels are associated with cardiovascular events in elderly patients with essential hypertension and can be used to assess potential cardiovascular disease risk.
elderly essential hypertensionlow density lipoprotein cholesterolresidual cholesterolcardiovascular events
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