首页|养阴止血方联合中药穴位贴敷治疗过敏性紫癜性肾炎的临床观察

养阴止血方联合中药穴位贴敷治疗过敏性紫癜性肾炎的临床观察

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目的 探讨养阴止血方联合中药穴位贴敷治疗过敏性紫癜性肾炎的临床疗效.方法 选取过敏性紫癜性肾炎患者 60例根据随机数字表分为两组,养阴止血方组 30 例、治疗组 30 例,测定患者治疗前后患者血清TNF-α、IL-8水平,及血肌酐(SCr)、超敏C反应蛋白(hs-CRP)水平,24h尿蛋白定量、尿RBC计数的变化.结果 治疗组的整体疗效有效率为 95.0%,养阴止血方组的有效率为 90.0%,两组比较差异有统计学意义(P<0.05);在减少尿蛋白、尿红细胞等方面,两组内治疗前后比较均差异有统计学意义(P<0.05);两组患者治疗后血清中TNF-α水平与治疗前相比均有所降低(P<0.05),两组间比较(P<0.05);两组患者治疗前血清中 IL-8、C反应蛋白与治疗前相比均有所降低(P<0.05),两组比较差异无统计学意义(P>0.05).结论 养阴止血方联合中药穴位贴敷在改善患者临床症状和减少尿蛋白、减少尿红细胞等方面优于单用养阴止血方,可通过调节紫癜肾患者免疫失衡保护肾功能.
Clinical Observation on the Treatment of Allergic Purpura Nephritis with Yangyin Zhixue Formula Combined with Traditional Chinese Medicine Acupoint Application
Objective To discuss the clinical effect of Yangyin Zhixue Decoction combined with acupoint application of traditional Chinese medicine in the treatment of allergic purpura nephritis.Methods Sixty sick persons with allergic purpura nephritis were selected and separated into two groups according to the random number table:the nourishing yin and hemo-static formula group(30 cases)and the treatment group(30 cases).The levels of serum TNF-α,IL-8,serum creatinine(SCr),high-sensitivity C-reactive protein(hs-CRP),24-hour urinary protein and urinary RBC count were measured before and after treatment.Results The entirely effective rate of the treatment group was 95.0%,and the effective rate of the Yangyin Zhixue Decoction group was 90.0%.There was a major difference between the two groups(P<0.05).In terms of reducing urinary pro-tein and urinary red blood cells,there were major differences between the two groups before and after treatment(P<0.05).The level of TNF-α in the serum of the two groups after treatment was inferior to before treatment(P<0.05),and the contrast be-tween the two groups(P<0.05);the serum levels of IL-8 and C-reactive protein in the two groups were lower than those be-fore treatment(P<0.05),and there was no obvious difference between the two groups(P>0.05).Conclusion The combination of Yangyin Zhixue Formula and traditional Chinese medicine acupoint application is superior to the single use of Yangyin Zhixue Formula in improving clinical symptoms,reducing urinary protein,and reducing red blood cells in patients with pur-pura,which may protect renal function by regulating immune imbalance in patients with purpura.

nourishing yin and stopping bleeding formulaAcupoint applicationAllergic purpura nephritis

杨雨萌、王珂、张春戬、谢俊霞

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黑龙江中医药大学附属第二医院哈南医院,黑龙江 哈尔滨 150000

黑龙江省中医药科学院,黑龙江哈尔滨 150000

养阴止血方 穴位贴敷 过敏性紫癜性肾炎

2024

哈尔滨医药
哈尔滨市医学会

哈尔滨医药

影响因子:0.697
ISSN:1001-8131
年,卷(期):2024.44(4)
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