Effect of Ultrasound-guided Regional Block Combined with General Anesthesia on Coagulation Function,Hemodynamics and Postoperative Rehabilitation in Elderly Patients with Femoral Fracture
Objective To investigate the effects of ultrasound-guided regional block combined with general anesthesia on coagulation function,hemodynamics and postoperative rehabilitation in elderly patients with femoral fracture.Method A total of 70 elderly patients with femoral fractures were prospectively selected as the study subjects.Using random number table method,these patients were randomly divided into treatment group A and treatment group B,35 cases in each group.The treatment group A was given resting combined general anesthesia,while the treatment group B was given general anesthesia combined with ultrasound-guided regional block.The hemodynamic indexes,oxidative stress response indexes,clinical indexes,VAS scores,coagulation function indexes and adverse reactions were observed and compared.Results There was no significant difference in hemodynamic indexes between the two groups at T0(P>0.05),while the hemodynamic indexes of treatment group B at T1,T2,T3 and T4 were significantly lower than those of treatment group A(P<0.05),while the CRP and COR indexes of treatment group B at T2,T3,T4 and T5 were significantly lower than those of treatment group A(P<0.05).At the same time,the NE index in the treatment group B was significantly higher than that in the treatment group A at T2 and T3(P<0.05),while it was significantly lower than that in the treatment group A at T4 and T5(P<0.05).After intervention,the clinical indexes such as anesthetic dosage,recovery time,laryngeal mask removal time and postoperative hospitalization time in the treatment group B were significantly better than those in the treatment group A(P<0.05).There was no significant difference in PT and APPT between the two groups at 12h after operation(P>0.05),while the Fbg index of treatment group B was significantly lower than that of treatment group A at 12h after operation(P<0.05).The VAS scores of the treatment group B at 1h,6h,12h and 24h after operation were significantly lower than those of the treatment group A(P<0.05).There were no serious adverse reactions in the two groups during the treatment,and the safety of the treatment plan was relatively good.After the intervention,the incidence of adverse reactions in the treatment group B was significantly lower than that in the treatment group A(P<0.05).Conclusion The clinical effect of ultrasound-guided regional block combined with general anesthesia in the treatment of elderly patients with femoral fracture is significant.It can not only effectively improve the oxidative stress response index,clinical index and coagulation function index of patients,but also reduce the VAS score,stabilize the hemodynamic index,and have fewer adverse reactions.It is worthy of clinical promotion.
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