Effect of Hepatic Arterial Chemoembolization on Liver Function,Tumor Marker Level and Prognosis in Patients with Primary Hepatocellular Carcinoma after Resection
Objective To investigate the effect of hepatic arterial chemoembolization in patients with primary hepatocellular carcinoma after resection.Methods A total of 124 patients after primary liver cancer resection were selected as the study objects.62 patients in the perfusion group received hepatic artery chemoembolization,and 62 patients in the embolization group received hepatic artery chemoembolization.Disease control rate,liver function,tumor marker level,median progression-free survival,overall survival and incidence of adverse reactions were compared between the two groups.Results After chemotherapy,the disease control rate of embolization group was higher than that of perfusion group(P<0.05).After chemotherapy,the levels of liver function indexes in both groups were decreased(P<0.05),and those in embolization group were higher than those in perfusion group(P<0.05).After treatment,tumor marker levels were decreased in both groups(P<0.05),and were lower in embolization group(P<0.05).After treatment,the median progression-free survival in embolization group was higher than that in perfusion group(P<0.05),and the overall survival rate in embolization group was higher than that in perfusion group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Hepatic arterial chemoembolization is effective in the treatment of patients with primary hepatocellular carcinoma after resection.It can improve the disease control rate,prolong the survival time,have little effect on liver function,and reduce the level of tumor markers.
万方数据
维普
