Analysis of Multiple Antibiotics in Water and Soil Based on HPLC-MS/MS
The accurate detection of antibiotic residues in the environment is important for the assessment of their ecological risk.A syn-chronous analysis of multiple classes of antibiotics in water and soil based on HPLC-MS/MS technology.Efficient separation and supertrace detec-tion of tetracyclines,macrolides and β-lactam antibiotics was achieved by optimizing chromatographic separation conditions and MS detection pa-rameters combined with solid phase extraction pretreatment.Method detection limit reached pg/L level,linear range was 0.1～500 μg/L,and spike recovery rate was 75.8%～95.7%.
HPLC-MS/MSwater bodysoilmany classes of antibiotics
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