含铕稀土功能抗菌材料的性能及抗菌机理研究
Study on Properties and Antibacterial Mechanism of Rare Earth Functional Antibacterial Materials Containing Europium
张春霞 1李璐 1孙丕智 1刘岗 1崔鸿亮 1郭鹏博1
作者信息
- 1. 天津包钢稀土研究院有限责任公司 天津 300300
- 折叠
摘要
研究制备了一种新型稀土功能抗菌材料,将含铕(Eu)的多金属氧簇(POMs,EuW10)与生物胺精胺(Spermine,Spm)共组装,EuW10 的荧光增强约 13 倍,抗菌性能由 61.34%提升到 100%.机理研究表明,EuW10 和Spm之间的协同效应增强了其对细菌的摄取能力,在细菌微环境中丰富的过氧化氢(H2O2)的参与下,组装体产生大量的活性氧(ROS),达到了高效抗菌的特性.
Abstract
A new type of rare earth functional antibacterial material was prepared,europium-containing polymetallic oxygen clusters(POMs,EuW10)were co-assembled with spermine(Spm),and the fluorescence of EuW10 was enhanced by about 13-fold,and the antibacterial property was increased from 61.34%to 100%.The mechanism showed that the synergistic effect between EuW10 and Spm enhanced its uptake of bacteria,and pro-moted the assembly to produce a large number of reactive oxygen species(ROS)with the participation of abundant hydrogen peroxide(H2O2)in the bacterial microenvironment,achieving excellent antibacterial performance.
关键词
铕稀土/抗菌材料/过氧化氢/活性氧Key words
europium rare earth/antibacterial material/hydrogen peroxide/active oxygen引用本文复制引用
出版年
2025
NETL
NSTL
万方数据