Analysis of pathogens of acute respiratory infections in children aged 6-15 in Bengbu City
Objective:To explore the pathogen spectrum composition of acute respiratory infections among primary and secondary school students in Bengbu City,and to provide basis for formulating effective prevention and control measures.Methods:From January to August 2022,1625 throat swab samples of influenza like cases were collected from the influenza monitoring sentinel hospital in Beng-bu City,including 233 samples from children aged 6-15 years old.About 10 samples from children aged 6-15 years old were collected each month,totaling 80 samples.FilmArray multiple nested PCR was used to detect 22 pathogens,and fluorescent quantitative PCR was used to detect influenza virus and COVID-19 nucleic acid.Analysis was conducted in terms of the types of pathogens of acute re-spiratory infection in children aged 6 to 15 years old in Bengbu,the composition of pathogens of acute respiratory infection in different months,the physical examination of pathogens of acute respiratory infection in different age groups and sexes,the characteristics of pathogens,and the real-time fluorescent quantitative PCR detection results of influenza and COVID-19.Results:28 pathogens were de-tected out of 80 respiratory throat swab specimens(35.00%).A total of 32 strains of 7 pathogens were detected,among which rhino-virus/enterovirus(37.50%)and influenza B virus(34.38%)accounted for a relatively high proportion.January and February 2022 were the peak of the B-type influenza epidemic,and there was no statistically significant difference(P＞0.05)in the positive rates of other pathogens detected between different months.There was no statistically significant difference(P＞0.05)in the positive rate of a-cute respiratory infection pathogens among different age groups and genders.Among the 28 positive cases detected,25 cases(89.29%)weresingleinfections,2 cases(7.14%)were double infections,and1 case(3.57%)was triple infections,with the highest proportion of single infections(P＜0.001).26 cases(92.86%)of viral infection and2 cases(7.14%)of bacterial infection were detected(P＜0.001).Conclusion:Rhinovirus/enterovirus and influenza virus are the main respiratory pathogens causing acute respiratory infections in primary and secondary school students aged 6-15 in Bengbu City.Except for influenza virus,there is no statistically significant difference in the positive rates of other pathogens such as rhinovirus detected in different peri-ods.
万方数据
维普
