Analysis of influencing factors of PICC catheter-related infections in hepatobiliary surgery
Objective:To explore the influencing factors of catheter-related infections(PICC)in hepatobiliary surgery and to devel-op corresponding prevention and treatment strategies.Methods:A retrospective analysis was conducted on the data of 258 patients who received treatment and had PICC catheters placed in the hepatobiliary surgery department of a hospital from January 2020 to March 2023.Based on the occurrence of PICC catheter-related infections,they were divided into an infected group and an uninfected group.Univariate and multivariate logistic regression analyses were conducted to identify the influencing factors of PICC catheter-related infec-tions in the patients,and a predictive model was established based on the influencing factors.A receiver operating characteristic(ROC)curve was plotted to evaluate the diagnostic performance of the model.Results:Out of the 258 patients,40 developed PICC catheter-related infections,including 20 local infections and 20 catheter-related bloodstream infections;61 strains of pathogenic bacteria were cultured and isolated from the blood of the infected patients,including 35 strains of Gram positive bacteria,23 strains of Gram negative bacteria,and 3 strains of fungi.Univariate analysis showed that there were no statistically significant differences between the two groups of patients in gender,previous surgical history,catheterization season,presence of cardiovascular disease,puncture site,puncture vessel,puncture method,catheter type,periodic catheter maintenance,history of phlebitis,and catheter blockage(P＞0.05).The rates in the infection group of age≥60 years,history of diabetes,more than 2 single catheterization punctures,using doub-le lumen catheters and catheter retention time≥7 days were higher than those of the uninfected group,and the differences were statisti-cally significant(P＜0.05).Multivariate logistic regression analysis indicated that the influencing factors of PICC catheter related infec-tion in patients with hepatobiliary surgery were age≥60 years,diabetes,the number of single catheterization punctures≥2,the use of double lumens of catheters and the retention time of catheters≥7 days(P＜0.05).ROC curve analysis showed that the AUC value of the prediction model was 0.865,with a sensitivity of 75.00%and a specificity of 86.70%.Conclusion:The incidence of PICC cathe-ter-related infections in hepatobiliary surgery is relatively high.Age,comorbidities,number of punctures,number of catheter cavities,and catheter retention time are all influencing factors.Clinical intervention should be carried out in advance to reduce the incidence of infec-tions based on these influencing factors.Constructing a predictive model can help screen high-risk populations for PICC catheter-related infections in clinical practice.
Peripheral vein central vein catheterizationPICC catheter-related infectionInfluencing factorsPreventionPrediction model
万方数据
维普
